Levetiracetam (Keppra) to help in some cases of RLS.

[Tim61]

Tim61,

I posted recently about withdrawing from Pramipexole, which I’m doing at the moment, not very nice.

My GP eventually discovered I was suffering with myoclonic jerks, not restless leg syndrome. I saw him yesterday’ & he has agreed to try keppra ( levetiracetam) 250mg at night. I took the first dose last night & had a better nights sleep, & not so much leg jerking, so I’m hoping this will continue.

I’ve posted because I’ve read this very good article about Keppra being used to help restless leg syndrome, & periodic limb movement in sleep.

Levetiracetam (Keppra) can be effective in the treatment of restless legs syndrome, with periodic limb movements in sleep: report of two cases; G.Delta Marca, C. Vollono & S. Mazza.

I know you guys, know your stuff about restless leg syndrome, & may have read this article, but thought it was worth posting for thoughs who have suffered augmentation from Dopamine antagonist, & are looking at other treatments rather than opioids.

[Madlegs1]

Very interesting. My newborn grandson is being treated with Keppra, for suspected spasm issues .( When he was born last week, I suspected rls) He quieted down when I stroked his head, and all tests have cleared him of any issues. But a major scare for all involved.

I did some research on Keppra, and it seems to be a fairly safe medication, compared with the alternatives.

There is an extended release form, which might well be useful in chronic rls.

Talk of Serendipity!🤗🤔

Thanks for posting. A very useful bit of information.

I wonder does Dr B include its use on his site. I'll have to check that out now.😣

[Hidden]

Interesting! Thanks for sharing! Unfortunately, I might have to switch my meds. soon. I will not use opioids to help, so I’ll look into this.

Thanks again!

[Dancingintherain]

Thanks for posting this hopeful bit of information. I will definitely look into Keppra.

[tinabuglaw]

Anyone try Keppra successfully?

[Lapsedrunner in reply to tinabuglaw]

There’s just been a post re this!

[Tinabugsu in reply to Lapsedrunner]

I can't find it, other than what is above. Can you tag me or something

[Lapsedrunner in reply to Tinabugsu]

Use the search icon and put in Keppra, should work, or just scroll through the recent posts.