PSP Association
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I am wondering about women who were on homone replacement therapy. Do you think that homones had anything to do with you contracting PSP? I was using bioidentical hormone cream in 2009 and the doctor I went to was into strokes and refused to prescribe me with estrogen cream. Consequently I suddenly stopped using it and developed PSP soon after. Now that I look back on this whole experience I wonder about if stopping suddenly had anything to do with me getting PSP.

6 Replies

hi lyndeleliss well i cant help you with that question mate but what about the male population that get it !!!!!!!! ]] but im sorry that you do have it \\ what will we say that they might have taken we are in an elite club only four in a million or only one in a hundred thousand people get it i believe it has no class distinction didnt Dudley More have it anyway whose to say that it was not the hormone cream nobody knows mate take care \\\\\ just another psp sufferer peter jones queensland australia but its a thought i suppose and we have to start somewhere


Hi Lynda,

I'm pretty certain that HRT did not play a part in my Mum getting PSP. As far as I know she did not take HRT. I think the statistics suggest that PSP is more prevalent in men than in women too but as Peter implies there is not enough known about this disease to be able to say for sure.



My wife June was diagnosed 7 years ago when she was 66 years young and was never on HRT she went through a normal menopause with no drugs she just put up with it and kept very physically active. June is currently at the final stage unable to communicate, speak, walk etc and her feeding is by syringe into the mouth with pureed foods but she is gaining weight at this time. She does know what is going on around her and still can manage a smile Good luck.


Wife has PSP no hormone replacement. I personally doubt something that obvious would slip by research neurologists.


Hi Lynda -the answer is "who knows" -there have been several discussions around statin drugs, head trauma etc being the cause. The medical community is linking PSP to several chromosomes. They think they have linked PSP to over active Tau proteins but don't understand the cause - again -no one knows for sure yet. So far it sounds like it is a genetic issue but that maybe certain drugs or trauma causes PSP symptoms to appear sooner rather than later. There are many medical articles out there on the web -try searching "progressive supranuclear palsy and tau protein" and see what you can find.

Hope this helps a little - I am sorry to hear of your diagnosis. We are all here to help!



Thanks for answering, Richard and Danielle.


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