Lupron Depot 90 day and Cosadex

[Geminidizz]

Has anyone stopped their hormone degermation trestment even though your Dr didn't approve? What were the side affects and did your libido return, long before did it take you before feeling your sexuality again.

[wallygator]

Actually, I did the opposite. I convinced my oncologist to leave me on ADT for six months after they wanted to stop treatment after some research showed that longer ADT treatment in combination with salvage radiation improved progression-free survival. I was on ADT for a full year. I may never know if this was a good idea. I have now been off ADT since the end of 2018 and had an undetectable PSA since then. It took about nine months after stopping for some semblance of desire and function to return.

Wally

[EdinBmore]

Firmagon, 1 mo, Lupron, 3 three mo duration injections. Last injection May 2019; should have started to dissipate by end of Aug 2019. Docs told me 6-9 mos before feeling better. Yeah, well. Btw, 25 IMRT, bracy boost, and ADT. GS 3+4, PSA 23, AS for 7 yrs.

Some men here seem to live through ADT without much reaction to it. Me? Not so much. I had a particularly bad ride with ADT. Really rough for me. Many side effects; none was good.

Re your question about libido returning. It hasn't. Testosterone dropped to undetectable level during ADT. It's taken 8 mos for T to roar back to 70. LOL. At doc apt in February, doc acknowledged that it might take 12 mos for T to return to pre treatment level (if it ever does return to that; I'm skeptical). So, hate to be a downer about all of this but...I'm still hopeful though. Btw, genital atrophy, no interest in sex, no ejaculate (obviously, given the treatments I had), can get semi hard on (taking Tadalafil, 5mg troche. And, am in Restore study out of U of MN. They provide Sildenafil as part of the study). Can get hard and can reach orgasm (but unsatisfying for me. Just not the same feeling at all. Sigh.) Use to btm but that's on hold, as it were, until I feel better (it's been 2 yrs! Yikes) Not sure how it'll feel and concerned about being "messy" since radiation treatments affected bowels (TMI, I suspect, but from 1-2 bm a day to 5-6 a day now)

So, hope others who had better experience than I, respond to your post; perhaps, give you an alternative perspective.

Good luck to you. Hope your journey is different than mine was.

EdinBaltimore