Hey Folks, I'm Richard, 58 years old, Gleason 4+5=9, no Metastasis detected with Bone and cat scans, although micro-metastasis are common with Gleason 9. Had external beam radiation (EBRT) and a high dose brachytherapy (HDRT) boost late 2019 and early 2020 last year. Total biological equivalent dosage (BED) was > 200. PSA is undetectable at this point and has been so since the HDRT. I've been on ADT for 14 3/4 months. (1st month was Degarelix, then 12 months Lupron, now back to Degarelix).
I want to try to reach 24 months of ADT. I know of the Nabid study thanks to Tall (Heroic, Generous, Knowledgeable) Allen, but want to attain 2 years minimum of ADT. Nguyen's comments, and Walker and others suggest that 2 years is minimum UNLESS the patient has other major health problems.
Side effects of the ADT are significant for me. After 14 3/4 months, I get tired every day in mid-day. If I then try to nap, I'm too tired to work, but too much awake to sleep. The depression is bad as well. I cry easily and frequently, and negative thoughts are very common.
Right now, I do aerobic exercise for ~40 minutes about 6 times per week. I'm on Lexapro for depression (10 mg), I'm trying to eat healthfully, taking vitamin D (4000 icu) and calcium supplement. I'm also trying to do this 16/8 diet and trying to reduce carbs. (But MAN I do cheat sometimes. It's like carbs are crack cocaine for me, and once I start I can't stop). I've lost about 20 pounds since I started eating more healthfully. I have 4 cups of caffeinated coffee per day, in the morning. (Otherwise healthy, and don't smoke nor drink). But I have about 9 months of ADT left to go.
PLEASE GUYS: what tactics are you using to deal with the ADT symptoms?
Nabid et al, sciencedirect.com/science/a...
Morris et al, sciencedirect.com/science/a...
Nguyen comments on Nabid study, onclive.com/view/radiation-....