Dozy Date. 😞: This morning, after a bad night, I... - PMRGCAuk

PMRGCAuk

20,301 members β€’ 38,032 posts

Dozy Date. 😞

SheffieldJane profile image
β€’101 Replies

This morning, after a bad night, I inadvertently took my 100 microgrammes of Thyroxine twice. Realised the moment it was down my throat. I had just taken yoghurt and was supposed to take 7 mgs of Pred. Not sure what to do now. I haven’t taken Pred because of all the Thyroxine coursing around. I will later.

Has anyone with the two conditions done this? Can it be put right? Should I just ignore it and carry on with usual doses tomorrow?

I dread a day with banging heart. Woke up at 4 am with a short lived pain travelling down the side of my jaw and a sore eye, same side.

Many thanks.

Poopadoop? Fount of all knowledge?

Written by
SheffieldJane profile image
SheffieldJane
To view profiles and participate in discussions please or .
Read more about...
101 Replies
β€’
Rimmy profile image
Rimmy

Beyond my 'medical' capacities SJ - but I think it will all be OK - I'm sure more informed minds will answer soon - try not to stress in the meantime and if you can and check with a pharmacist or medical helpline.

Grants148 profile image
Grants148

Oh dear Jane,l take Thyroxine and am always worried l may take a double dose ,especially with the brain fog l seem to have,lt probably will not do any harm but perhaps your local pharmacist can give you advice on this,also just do not take any tommorrow then things should hopefully even out.

SnazzyD profile image
SnazzyD

I’d call my pharmacist

Celtic profile image
CelticPMRGCAuk volunteer

Me, too, Jane!

SheffieldJane profile image
SheffieldJane

Thank you. On line doctors seem to think it’s not a big deal ( if they are doctors 😬). It was the Pred angle I was concerned about. Poor old liver.

yogabonnie profile image
yogabonnie in reply to SheffieldJane

most loved about this whole thread.... "if they are doctors".

SheffieldJane profile image
SheffieldJane in reply to yogabonnie

Well they were wearing white coats in their photos. πŸ˜‰

MamaBeagle profile image
MamaBeagle in reply to SheffieldJane

My son when a young'un thought that a white coat was all it took to be a doctor! In all seriousness he once said to me "Mum" yes "when I grow up I won't be able to be a doctor you know" Why ever not said I " I haven't got a white coat" said he. That wasn't the only thing he couldn't become. In a conversation he also thought that all he needed to play tennis like McEnroe was a headband and wrist bands.......and a racket of course!

Constance13 profile image
Constance13 in reply to MamaBeagle

What did he end up as? (If it’s not too private a question).

MamaBeagle profile image
MamaBeagle in reply to Constance13

He's a plumber!

Constance13 profile image
Constance13 in reply to MamaBeagle

More use than some of the doctors we hear about then!πŸ˜€

πŸ’πŸ’

PMRpro profile image
PMRproAmbassador in reply to MamaBeagle

I keep trying to persuade the grandsons to do plumbing. One wanted to do medicine and the other a paediatric nurse. Their exams aren't encouraging for either - which in the case of the would-be doctor (good but not straight As) is a relief...

Rugger profile image
Rugger

Have you thought of getting one of those 'wallets' for your weekly tablets, with days of the week and times of the day? I'm sure I've read that PMRpro and others have them. Then you need to sit down only once a week and dish out all the doses into the right compartments. Jobs a good 'un, as Mark would say!

No specific advice to offer, apart from speaking to a pharmacist or 111. x

SheffieldJane profile image
SheffieldJane in reply to Rugger

I do that Rugger, I’ve got daily containers with times of day. I have recently started taking Thyroxine first and Pred with Yoghurt an hour or so later. It’s the change I expect. Thanks

Rose54 profile image
Rose54

Hi

I have done the same some time ago I contacted 111 and they said not to worry as some people who have thyroid problems are advised to take their dose weekly not daily .

Said may have a few palpitations but should be ok advised to take dose as normal next day .

SheffieldJane profile image
SheffieldJane in reply to Rose54

That’s useful. One poor soul on the thyroid site had taken a deliberate massive overdose and was ok thankfully.

Daisychain12 profile image
Daisychain12 in reply to SheffieldJane

Blimey.

Xanthe12345 profile image
Xanthe12345

Don't worry it might make you a bit hyper .....and should'nt interfere with steroids. I was on 175mg daily a few years back. Try the pill section boxes. Set mine up for the week on a Saturday afternoon.

Lots of water as well

πŸ‘

SheffieldJane profile image
SheffieldJane in reply to Xanthe12345

Do you take your Saturday pills before you start sorting pills for the week? I think that’s what muddled me. I can’t believe anyone actually employed me. πŸ˜…

Xanthe12345 profile image
Xanthe12345 in reply to SheffieldJane

Hi Jane I start the day with heart pills at 7am. Then thyroxine at 8am. Then pred at 9 am with food. Unless I have to be out early in which case I squeeze them up. In the evening heart pill at 6pm aspirin at 7pm and blood pressure pill at 8pm.

Have had add Mirtzapine at 10pm.

How I wished I could chuck them all out of the window. Lol

I find filling pill boxes are the only way to keep check on which ones I have taken....with pred fuzzy head

Hope you feel ok πŸ˜ƒ

SheffieldJane profile image
SheffieldJane in reply to Xanthe12345

I feel rather suspiciously good Xanthe.

Xanthe12345 profile image
Xanthe12345 in reply to SheffieldJane

Oh dear! Perhaps you need to take 200mgs daily and chuck the pred out......if only x

Patience47 profile image
Patience47 in reply to SheffieldJane

Jane, don't feel bad about that as the same exact thing has happened to me. Re- Saturday and med bar.

SheffieldJane profile image
SheffieldJane in reply to Patience47

Bit wakeful but unscathed. Live to fight another day.

Daisychain12 profile image
Daisychain12 in reply to SheffieldJane

Oh Jane I was once in charge of multiple million dollar accounts. I can’t even read my statement now. I am bovine.

Jeannie29 profile image
Jeannie29 in reply to Daisychain12

Oh Daisychain12 I was the same, retired 2 years ago at 74, since then been downhill all the way. There was a time when I wouldn’t have the word OLD mentioned haha

DorsetLady profile image
DorsetLadyPMRGCAuk volunteer

Oops! Can you take the Pred now, if you haven’t already? Or will that mess up other tablets later in the day!

SheffieldJane profile image
SheffieldJane in reply to DorsetLady

I did, I got a tremendous PMR pain in my shoulder which reminded me that it was not to be trifled with. It’s the keeping Thyroxine on an empty stomach well away from other drugs. Supposed to be good in the evening, I may do that but the insomnia may return and there’s Amitriptylin.

I hope my small crisis is of use to someone else. If I change a routine everything goes to pot. Thanks.

DorsetLady profile image
DorsetLadyPMRGCAuk volunteer in reply to SheffieldJane

Yes it does very easily.

We do many things on automatic pilot, and then if we think about it afterwards, we’re not 100% sure what we’ve done.

Guess it makes us different from a machine! But a bit of a pain in the proverbial sometimes!

🌹

SheffieldJane profile image
SheffieldJane in reply to DorsetLady

🌞

morrison profile image
morrison

Don't stress. These thingshappen. We can all have pred head at the best of times. X

SheffieldJane profile image
SheffieldJane in reply to morrison

How are you my old friend and star grandma?

morrison profile image
morrison in reply to SheffieldJane

How dare you.... less of the old. Ha ha.....πŸ˜…. Holding good at 10 most. Back down to 9mgs next week. Same old same old. Hope you're feeling less stressed and had your pred. Xx

SheffieldJane profile image
SheffieldJane in reply to morrison

I did take it. I’ve got a pain in my eye though. The same one that woke me in the early hours. Maybe some kind of hay fever thing, it’s watering too.

SheffieldJane profile image
SheffieldJane

Thanks for the helpful responses everyone. This is a fantastic, trustworthy resource. Xxx

Jeannie29 profile image
Jeannie29 in reply to SheffieldJane

I agree, don’t know how I would cope without it now x

OHHHHHH SheffieldJane, Are you okay???? We've been out at the cinema and I'm just seeing this post!

SheffieldJane profile image
SheffieldJane in reply to

I overdosed but all was well, just took Levothyroxine twice.. want to come to a pyjama party? I am going to be up all night. What did you see?

Hollyseden profile image
Hollyseden in reply to SheffieldJane

Hahaha

in reply to SheffieldJane

Ohhhhh Jane, I was worried! I don't know what Levothyroxine even is, but it didn't sound like something you should take TWICE! Thank goodness you are okay!!!! Don't do that again, please!!!!

suzy1959 profile image
suzy1959

I take Pred. in the morning, Amitriptyline at 7:30 and Thyroxine at bedtime. I read somewhere that taking Thyroxine in the evening was a good idea and it fitted with the whole regime- seems OK and actually this year, I needed to reduce my Thyroxine for the first time in many years- could it be because it is more effective at night? Who knows!

SheffieldJane profile image
SheffieldJane in reply to suzy1959

I read that too. Something Poopadoop posted I think. I think I’ll try but I worried about it keeping me awake which the double dose is doing. It doesn’t like any other drugs or anything on the stomach though. I am full of Rooibos tea at bedtime and that’s when I take the Amitriptylin for sleep.it’s maths and I hate maths.

Daisychain12 profile image
Daisychain12 in reply to suzy1959

Suzy do you still do this? Maybe I should take thyroxine at night.

suzy1959 profile image
suzy1959 in reply to Daisychain12

Yes, I do. I think it's easier to separate drugs as much as possible, but who knows if it makes any difference!

karools16 profile image
karools16

Jane, snap, snap, snap! Friday morning, took my 6pm warfarin at 8am, i.o. Pred. Also, only realised after swallowing. Rang pharmacist to find out when next dose warfarin. He said to be sure to take the Pred. Take warfarin Sat at 4pm, and DON'T DO IT AGAIN!! YOU'D THINK AFTER ALL THESE YEARS, i'D KNOW BETTER. I have the dosette next to computer, and take Pred whilst reading the forum. Lack of concentration.

Yes. 3 weeks ago I took a double dose of thyroxine. Like you say it was just sliding down my throat when I realised. I actually just felt really rough that day. Wasn't sure if I imagined it. But I am down to 50mg so perhaps not a big deal for me. Hope you have survived the day.

SheffieldJane profile image
SheffieldJane

I am on 100/125 microgrammes alternate days, it did make me feel a bit wired. It made a nice change from sloth to dung beetle ( energy). But seep seems a forlorn hope. Would you take another 100 tomorrow and maybe leave off the 25s?

in reply to SheffieldJane

I would be tempted to start rotation at 100.

Hollyseden profile image
Hollyseden

Sorry about your mistaken dose. On a lighter note, once upon a time, many years ago, our puppy ate a bottle full of thyroxine. Mad panic phone calls to emergency vet followed. I was reassured that puppy would be fine and she was. My 5 year old daughter however had to do without her dose that night πŸ˜‹

SheffieldJane profile image
SheffieldJane

Trouble is the puppy is a Great Dane now.

in reply to SheffieldJane

πŸ˜‚πŸ˜‚πŸ˜‚

You okay and did you get some sleep?

Hollyseden profile image
Hollyseden in reply to SheffieldJane

Belatedly spotted your reply.πŸ˜‚πŸ€£πŸ˜‚ Imagine my poor wee puppy turning into a great Dane overnight 😲

yogabonnie profile image
yogabonnie

are you you okay now?

Marlenec profile image
Marlenec

It's a nightmare juggling the pills around. But the replies seem to be it's not too drastic. Hope your body soon sorts itself out and tell it you won't do it again! Try to catch up on sleep.

PMRnewbie2017 profile image
PMRnewbie2017

Hi Jane. I've checked some toxicology sites and overdoses of less than 500 mcg do not require medical intervention or treatment with activated charcoal. Any aches or pains or fevers which you may develop must be treated with paracetamol NOT ASPIRIN. Aspirin displaces T4 and increases serum levels. Hope this reassures you.

SheffieldJane profile image
SheffieldJane in reply to PMRnewbie2017

Thank you for going to the trouble of looking on toxicology sites. I never thought of that. Chastened but fine this morning.

SnagglePuss profile image
SnagglePuss in reply to PMRnewbie2017

That's interesting about Aspirin being a no-no with Thyroxine. I find analgesics which contain Asp. work best for me! Will have to research further - thanks πŸ™„

SheffieldJane profile image
SheffieldJane in reply to SnagglePuss

I didn’t know either. I have only had Graves Disease for 30 years 😬

SnagglePuss profile image
SnagglePuss in reply to SheffieldJane

Well it's probably not fatal then! 😁

SheffieldJane profile image
SheffieldJane in reply to SnagglePuss

The last time I looked I was still here.

Marymon profile image
Marymon

Perhaps what we all need with AI disease is the other AI artificial intelligence πŸ€–

Telian profile image
Telian

Can't help you with this drug but hoping you're okay now

Jo1947 profile image
Jo1947

Hi Jane, I have one of the weekly pill boxes and it tells me what I have or havnt done with my pills, couldn’t remember any of it otherwise. I also take 100mg of thyroxine but have taken it in the evening, well away from all the other tablets. Have done this for last 4 months and it seems to suit me. I have gone the other way to you, many times and forgotten to take one, the pill box helps me with that now. I’m sure as the day passes you’ll be ok, best wishes

El50 profile image
El50

No but last week I took 1 extra 1mg. Pred. instead of 100mc. of thyroxine for 3 days by mistake before I realised ---felt great!!!

SheffieldJane profile image
SheffieldJane in reply to El50

I was fine too but awake looking for friends at 4 am. πŸ˜€

El50 profile image
El50 in reply to SheffieldJane

Hope that you sleep well tonight.

SheffieldJane profile image
SheffieldJane in reply to El50

Thanks, I think I will.

sharonnorfolk profile image
sharonnorfolk

Hi, I was told by GP that I should take the prednisolone in the morning and not to take my thyroxine for at least 5 hours afterwards. Hope that helps. So pred for early breakfast and thyroxine or lunch statins for supper!!! How exciting.

SheffieldJane profile image
SheffieldJane

The only time that I am sure that I have an empty stomach is first thing in the morning. 5 hours! How can we achieve that? I have been leaving about 90 minutes. Then there’s the Adcal ( not to be taken near Pred). It needs a better brain than mine to work out. I have taken Thyroxine wrongly for 30 years. It is a wonder I am still here!

Lee1945 profile image
Lee1945

You should have immediately phond your GP

SheffieldJane profile image
SheffieldJane

Thanks Lee1945

altywhite profile image
altywhite

I wouldn't worry too much Jane, it's only one dose and at the worst you may feel a bit lively, shall we say!! Hope you took your pred as normal though and the regular dose of levo the next day. You're on a lot of the same meds as me and I have the little boxes for my tablets...the more tablets I was on the less I trusted myself to get it right!!! I take my levo as soon as I wake up along with Omeprazole and Vit K2, the about an hour later, after yoghurt or something I take my pred.....then 2 hours after that it's the Adcal!! :-) Take care. xx

altywhite profile image
altywhite in reply to altywhite

Oops....dozy me...just noticed that all this went on 2 days ago!!! Ah well...haha..glad all is well!! :-) x

SheffieldJane profile image
SheffieldJane in reply to altywhite

Appreciated though altywhite. I am here to tell the tale, as worn out as ever.

altywhite profile image
altywhite in reply to SheffieldJane

Yes, the worn out status just won't go away will it?? I'm managing to taper slowly.....slower than snail's pace I think!! But I don't feel too bad except for the darned tiredness!! One day.........:-) x

SnagglePuss profile image
SnagglePuss in reply to altywhite

At annual meds review with pharmacist (used to be Dr) I was told I shouldn't take levothyroxine at the same time of day as Omeprazole. Have been taking them together 1st thing in the morning for over 30yrs! Will be interesting to see if I notice any positive change πŸ™„

altywhite profile image
altywhite in reply to SnagglePuss

That's interesting Snagglepuss!!! I've been taking my Omeprazole at the same time as my levothyroxine since I started on the pred!! (over 3 years now) Can't say i noticed anything different and my levels have been ok. (been on levo for around 25 years) I've just started a new 'regime'!!! I'm taking the levothyroxine last thing at night now then I can take my pred earlier in the morning!! Who knew this would be so complicated??? :-) :-)

Daisychain12 profile image
Daisychain12

Oh gosh what’s this about Jane? Following thyroid cancer I too have to take thyroxine and pred in the morning. Are they incompatible ? I just swig them down. Ohhhhhh dear.

PMRpro profile image
PMRproAmbassador in reply to Daisychain12

There is no direct interaction between them - but being on pred may have an indirect effect on thyroid function via the HPA axis (the hypothalamus, pituitary and adrenal set-up) and thyroid stimulating hormone in particular.

But many patients are told to take thyroxine on an empty stomach - because a lot of foods, including milk, affect absorption. And since pred is better taken with food - that gives you a direct contraindication straight away. Not a problem - unless you want to take your pred very early with food so it is working by the time you get up. You wake, take your thyroxine, wait an hour and then have breakfast and your pred.

A lot of people who have other morning medications take their thyroid medication at night - well after their evening meal. And find it works well - some find it even works better.

MamaBeagle profile image
MamaBeagle in reply to PMRpro

Do many PMR sufferers get offered consultations with an endocrinologist PMRpro? Just wondering ...........

PMRpro profile image
PMRproAmbassador in reply to MamaBeagle

Not normally - but they should be if they suffer any symptoms of adrenal insufficiency while reducing slowly below about 5mg. One endo told a senior member of the charity that HE was of the opinion we should all see one. Others endos just snort and ask why the patient is there.

MamaBeagle profile image
MamaBeagle in reply to PMRpro

Thank you for that info. I was beginning to wonder why it's not the norm as the endocrine system seems a bit like the Underground - inter - related, interconnected with knock on effects. And so many people on the site seem to have other endocrine problems already!

PMRpro profile image
PMRproAmbassador in reply to MamaBeagle

Exactly - and it should be an integrated service, a team. But it isn't. It probably was 25 years ago - in the days when consultants talked to one another about patients, But now they can't even refer sideways, there is this utterly stupid concept of referring back to the GP who then has to refer to the new specialist. Adding months to the patient journey to a diagnosis.

MamaBeagle profile image
MamaBeagle in reply to PMRpro

And when they reinvent the wheel which no doubt will - they'll think they are so imaginative and have created something startlingly new!

piglette profile image
piglette in reply to PMRpro

My father blames it on the integrated dining room! In the good old days consultants had a separate dining room and would discuss cases over lunch and often sorted things out then. The powers that be then decided that this was wrong and everyone should share a dining room, so consultants were mixed up with everyone else and stopped discussing medicine but probably now gripe about pensions, Brexit, ......

PMRpro profile image
PMRproAmbassador in reply to piglette

... and the car parking...

piglette profile image
piglette in reply to PMRpro

Forgot that one!

PMRpro profile image
PMRproAmbassador in reply to piglette

When OH worked at Durham they were buiding the new hospital - which had not only fewer beds but also fewer parking spaces for everyone. EVeryone was to use public transport!!!! They had a consultants' meeting every month - at least half the time was spent complaining about parking. Month after month after month...

piglette profile image
piglette in reply to PMRpro

I know the problem. I suppose I am just as guilty. My brother has a theory if they organised the appointment system better fewer parking places would be needed and also less waiting room space. I could not believe it when I had to turn up on a Sunday morning at 7.30am for the op on my leg. I then sat all day and was sent home as they could not operate until 7.30pm. Did they really have that many people coming in for plastic surgery as emergencies on a Sunday? You see these things on TV and they spend their time talking about beds or lack of them. They then have some young girl rushing around organising them, who really has not got a clue although she is backed up by the continuous meeting, while you have world class surgeons sitting around or giving up for the day and wandering down to the pub.

PMRpro profile image
PMRproAmbassador in reply to piglette

Perhaps not for plastics - but they only had a limited number of theatres staffed and it or both were needed... Or no beds for post-op/in event of a problem - even more likely.

piglette profile image
piglette in reply to PMRpro

I was not the only one who sat around all day, next to the kitchen and we were nil by mouth! They must have known in advance how many theatres they had and have some idea of beds, particularly as they try to clear people out on Fridays. I am sure they could improve the admin.

PMRpro profile image
PMRproAmbassador in reply to piglette

I'm sure it could - a start would be having medically qualified people doing the admin! Instead of Tesco managers...

piglette profile image
piglette in reply to PMRpro

That is what all my medical friends say. I am not sure they use Tesco managers, they do not seem to be that well qualified.

PMRpro profile image
PMRproAmbassador in reply to piglette

There were in the early days - but the pay wasn't good enough...

altywhite profile image
altywhite in reply to PMRpro

That’s interesting about taking the thyroxine at night!! I might try it because it would mean I could take my pred earlier than I do now. I’m afraid I’m not an early riser so it might suit me. 😊

PMRpro profile image
PMRproAmbassador in reply to altywhite

This is a link to a study:

ncbi.nlm.nih.gov/pmc/articl...

and this is an article from an endocrinologist which explains it in simple language

markvanderpump.co.uk/blog/p...

SheffieldJane profile image
SheffieldJane in reply to PMRpro

Thank you for this useful link. Never in my 30 years of Graves Disease was I advised of any of this. Perhaps I am not a depressive after all.

PMRpro profile image
PMRproAmbassador in reply to SheffieldJane

I'm sure I have written about it before - I know several people who have benefitted from switching times and found other things improved. And depression is a common aspect of autoimmune disorders of all sorts.

ncbi.nlm.nih.gov/pmc/articl...

altywhite profile image
altywhite in reply to PMRpro

Thanks for this. I'm giving the night time thyroxine a try!!

PMRpro profile image
PMRproAmbassador

Exactly - and they get paid for the hours they work - which is more than can be said for the NHS at present.

SheffieldJane profile image
SheffieldJane

I have altered my way of taking Thyroxine following this advice and I feel remarkably better. It doesn’t bear thinking about really.

You may also like...

Up date and constipation

thought things would be fine as they are with my preds and other meds, everything went well with...

Out of date Prednisolone tablets

taper plan. I have quite a few unopened packets of pred of 5mg and 1mg tablets - mostly because...

starting date pred for GCA.

years ago, whilst working as a live-in carer, I woke up with the feeling my head was beingchopped...

Past my sell by date!

accumulation of annoying ailments is just getting me down . The prospect of trying to get a night’s...

Check Prednisalone sell by dates! 🐿

have been keeping for odd taper amounts like 2.5 mgs. I have just noticed that they all expire...