The blood test result shows no antibodies in my blood so will have to look elsewhere for the cause of the fearful itching, the holes in my skin and I can't use BP as an excuse for having the second infusion of Zoledronic Acid. Once my Rheumatologist had accused me of causing the lesions on my lower legs by scratching, I've been looking for an excuse not to have his alternative to ZA which was Denosumab, which had fewer side effects about 30 to ZA's 112, but I'm sure learned one's on the forum said with the second infusion was unlikely to get the same side effects or if one did they were less severe. The Dermatologist diagnosed pitted Oedema on both legs and has asked for a full vascular assessment and suggests a venous ultrasound as the first line investigation. I've got varicose veins as well compliments of Klinefelters. So the investigation goes on!
I'll let you know if I ever find what's causing the problem. Anyway I thank all who responded to my post I did so appreciate your contributions.