Date:
June 27, 2018
Source:
University of Calgary
Summary:
A team of scientists has discovered what could be a new option for these hard to treat patients. A drug usually prescribed for depression appears to effectively stop progression of Primary Biliary Cholangitis (PBC).
sciencedaily.com/releases/2...
journals.plos.org/plosone/a...
Certainly as the Researches said: more study on the effects of Mirtazapine (an atypical
antdepressant) on PBC is needed.
Betonarme...that is great news. Thanks for sharing 🤗
👍🤞🤪😳🙄🙂🤗😉😊
Hello,
I can't understand why more friends on here aren't thrilled about this. I sent those links to my doctors. 👏👏👏👏👏👏. Thank you for posting that information. Here's hoping it leads to something even more promising and concrete. I have given mirtazapine to my cats before. I got it from my Vet. It stimulates appetite. I have a few old picky cats. They sometimes won't eat. Unfortunately, that is a side effect of mirtazapine. But, I'll deal with that if it can halt progression of PBC.
Stella❤
I agree. That could be s great breakthrough. I could use extra lbs😀. I’m putting it on list of questions for hep.
Dear Ktltel,
I think the main reason many of us are unhappy about it, because, without explaining the whole reason behind the antidepressants use, somebody is trying to take advantage of us by hooking us on something dangerous in a long term, absolutely unnesessarily and addictive, adding another problem to the ones we already have.
Know people whose daughters while going through puberty being taking to the doctors..and doctors were prescribing "temporarily antidepressants" to easy the symptoms..These girls are now in their 30th 40th...struggling with antidepressants addiction and some othe related problems, including liver ones..One of the side effects of antideppressants is a liver apparently...
Hi Betonarme,
I agree this is good news and will mention to my Dr. tomorrow when I go. I did see this few months back and someone mentioned they were on this and it had bad side effects.. I don't remember who it was, but to me, it is worth a try!
Anyways I came across an interesting article as well. Check it out when you get a moment. All about diet and gut.
thehealthyhomeeconomist.com...
Thank you Donna. I have believed for a long time it maybe something to do with the food we put into our bodies.
Hi Donna
I now saw that you've posted about this study few months ago.
I got aware of it about 1 month ago and was not sure whether I should post it here or not. At the end I decided to post it.
Earlier this year there was also paper from Yale scientists in Science magazine claiming the relationship of gut microbiome and translocation (leaky gut) of certain bacteria to other organs and as a root cause of autoimmunity in general. I later found out that this is not a new hypothesis but what maybe new is that yale scientists claim to cure with either an certain antibiotics or vaccination. But I think there is still not some solid results here
Promising article, thank you for posting, let’s hope it gets some recognition and the further reasearch.
This sounds great, but antidepressants are serious stuff for a lot of reasons. I respond to Ursodiol well and have to say after looking into this, if it is offered by my doctor I will say "Thanks, but no thanks." Perhaps I'd feel differently if I was a nonresponder, but check out these side effects: drugs.com/disease-interacti...
Wow! I read this. Glad you brought it up😊
Among other things, there is a history of bipolar disorder on both sides of my family which if you follow holistic health, like autoimmune disorders may be triggered by leaky gut, imbalances in the microbiome, nutritional and/or environmental triggers. Depression definitely is. I'm all about finding and eliminating those triggers naturally, if possible. So far exercise and significant dietary changes along with Urso has been working for me.
What kind of diet are you following?
It is a biggest problem to decide...
As proper liver diet promotes healthy carbs mostly
Next to none protein or fats...
Would you please share your experience
Thank you!
I think the kind of “liver diet” you are mentioning is intended for people who have cirrhosis.
I drink lots of filtered water, a wide variety of veggies, healthy fats, nuts, seeds. Broccoli, cauliflower, beets, sweet potatoes, onions, garlic, kale, mushrooms, carrots, celery, spaghetti squash, eggplant, zucchini. I roast a chicken every couple of weeks and sometimes make soup from the carcass. I eat red meat occasionally, fish, shellfish (I did give up oysters), canned tuna and salmon. It's not uncommon that I eat a fully vegetarian meal. Tonight I had gluten free pasta with a sauce made with red bell pepper, onion, garlic, mushrooms, and eggplant, with a bit of pasta sauce. I don’t eat gluten but do eat other grains. Quinoa, brown rice, corn, oatmeal.
I avoid dairy but do eat sheep and goat cheeses and sometimes have some mozzarella or cheddar. I try to eat non-GMO grains and organic produce but I’m not super strict on that. I rarely eat processed foods. I also eat a variety of fruit and have a superfood and vegan protein shake every day. Finally, I don't eat many sweets and other than the occasional chocolate bar rarely eat anything with processed sugar. The only sweeteners in my house are raw honey and Vermont Maple Syrup.
I drink coffee and alcohol, usually red wine.
Thank you so much for detailed explanation!
I have similar diet plan with more restrictions.
No dairy of any kind, 99 percent gluten free, some fish, some chicken, no broth at all
Trying to stay away from alcohol and coffee now, very little nuts, no beans and peas, very little cruciferous veggies, oats, buckwheat, rice etc
Some dark chocolate-not much
Really crave wine sometime)
My hepatologist told me the one thing they know for sure on the nutritional front is that coffee is liver protective. Enjoy coffee!
How did you come about all those restrictions?
Ive heard of this, but the problem is coffee makes me super nervous and anxious((
So, definitely affects my nerves(
Plus,,i am taking homeopathy, and coffee is antidote(((
And i like the taste of it!!))..((
Uups, havent noticed your question)
Just watching my body reaction to certain foods, reading a lot about special diets for special conditions. I am russian, the diet treatments were very advanced over there always. The first thing doctor will tell you it would be about special diet for your condition.
The very famous is the one which is developed by one scientist, will try to remember the name and will send you this , has numbers and letters,,for pretty much all the major conditions. He was German i think..will check it out and send you
Oh man, yeah. Those are VERY bad side effects. And quite a few too. 😔
Well, they're on the right track. Hopefully they can figure it out..... soon. Thank you for that information.
Stella
Ditto...I’m out!🤗
It is very possible, that antidepressant will slow the progression of PBC. Why? Because there is a strong stress-liver connection. As soon as we get stressed adrenaline will start working on damaging the liver. Antidepressants will do their work , will prevent us from getting worried and stressed)
But...why not to try more natural approach to manage stress?
There are lots of options. Homeopathy, etc.
The studies are always ordered and paid by somebody-pharmaceutical manufacturers of antidepressants in this case.
But,,overall,,,very right thing to take control over your nervous system in order to heal the liver.
Sorry, just saw the article about the guts /autoimmune connection.
Very nice one.
But..not sure it will be suitable for us, people with compromised livers, as diet is solely based on fats, protein and fiber., which are not advisable in these amounts for problematic livers.
Good info on PBC symptoms and treatments
Methylprednisolone - PBC
PBC Stage 0, no medication 
PBC Foundation Webinars
