Anyone experiencing constipation while taki... - PBC Foundation

PBC Foundation
7,592 members6,458 posts

Anyone experiencing constipation while taking ursodiol?

Hello all. I've been newly diagnosed with PBC. I'm also dealing with breast cancer at the moment. I was put on 300mg ursodiol three times daily, & have been taking for 2 weeks. I was concerned I'd have intestinal issues taking this medication, but it's been the opposite. It's causing constipation instead. I never had an issue with this before as my diet is healthy. I'm wondering if anyone else had this issue with ursodiol? If anyone has any advice I'd greatly appreciate it!

This site has been a God send!

Thank you!

12 Replies
oldestnewest

This is from the Mayo Clinic on possible side effects of urso and constipation is on list. Try to drink more water & eat more fiber: fruits, vegetables, oatmeal etc. That will help.

Sorry you are going through so much right now. Stay strong & this group is here for you.

mayoclinic.org/drugs-supple...

2 likes
Reply

Thank you very much! This group has been incredible & im so grateful it's out there! While there's loads of info/support for breast cancer (& lupus, which I was diagnosed in 2005) there's very little on PBC. It makes such a difference knowing your not alone.

Take care of yourself!

❤️

1 like
Reply

Yes i find lactoluse good and fibogel

1 like
Reply

Hi and welcome, I was diagnosed in 2006 and seem to have periods when I am constipated even though I have a high fiber, high vegetable diet. I find that salad usually sorts that out for me or I use Lactulose.

best wishes

Reply

I only have constipation if I take codeine for pain relief...then I take lactulose..a small dose and it works very well. I have to take it if constipated for more than two days as I have cirhossis now.

You have a lot to deal with, so the very best.

Reply

Yes i take a stool softener it usually works.

Reply

Hi.

Taking into account the health problems that you have but also the need to take the medication, I also believe that you should drink more liquids, ingest more fibers and, if possible, avoid laxatives.

You need, above all, relax. The body needs also to adapt to the new medication. The initial phase of knowledge of PCB generates a great stress but you will see that, over time, you will almost forget that you have this news condition (not forgetting the medication, of course).

Greetings

1 like
Reply

i do. My doctor gave me a drink to take. I have had this before the medication. God is with you. Never leave you. Im in pain and praying through it. It was maylox.

Reply

I was taking Metamucil 1X per day to counteract constipation but after going gluten free I've found I no longer need it.

Reply

Since starting Urso in a January, I too have been constipated. I drink plenty of water eat fruits and veggies and after 3 days of not going, I take senna plus 4 tablets and I finally have relief. It’s such a miserable feeling when you have this problem but it can be dealt with.

Reply

I had been constipated before urso (started 2 weeks ago), since the medication my bowel movement has been improved that becoming regular.

Reply

Oh my yes for at least 20 days I stopped it.. I’m scared now though

Reply

You may also like...