Hi, I'm 33 years old and I have stage 1 PBC. I've been on 900 mg of Urso every day for the past 5 months. My Alkaline Phosphatase is now back in a normal range, so the Urso is working, thankfully. Four years ago, my GI doctor discovered the anti mitochondrial antibodies in my blood. At the time, the titer was around 37. Throughout the last four years, it has slowly increased to 78. Then I had a physical last week, and my bloodwork says that my AMA's (antimotichondrial antibodies) are down to 51.2. I am baffled- is this normal? I thought that they only increased over time?