Ursodeoxicolic Acid...: - PBC Foundation

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Ursodeoxicolic Acid...

PBCRobert profile imagePBCRobertPartner180 Voters

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17 Replies
deedee profile image
deedee

Urso for me has improved the quality of life. As I understand it, the breaking down of the toxins in the liver and acting as a 'flush' as now stopped the dreaded itch but it took a long time to get the dosage right, (which is according to each individual). I would like to say that many of us Do experience a little weight gain when taking urso and it seems to be accepted and expected but its a small price to pay when our skin is still intact and itch free. My own personal opinion.

Cathyjo profile image
Cathyjo in reply to deedee

I lost weight and don’t want food!

JerseyChris profile image
JerseyChris

Just a thought as the dose of Urso is based on weight when one loses a couple of stone should we reduce our dosage? Maybe a question for the medics.

PBCRobert profile image
PBCRobertPartner

Those of you with whom Urso didn't agree. I would be interested in this. Urso's job is to flush bile out of the system. It really only has one mechanism for doing this, therefore the runs can be a short term feature of taking Urso. It may well be that instead of "Urso not agreeing with you", that it may actually be serving its function within the body.

wobblechops profile image
wobblechops in reply to PBCRobert

Urso didn't give me the runs, it gave me chronic indegestion!

ho11y profile image
ho11y in reply to PBCRobert

Hi, I was prescribed Urso when diagnosed in 2008. It was fine for a couple of days, then my system completely seized up, basically I could not move my bowels for over a week, and this was every time I tried to take Urso. I have since been diagnosed with autoimmune hepatitis and seemingly it is that, that stops me tolerating Urso.

lucretia profile image
lucretia

have been on urso for 6 years, and the itch is now back with a vengence!!!!!!!!!

Susiecoalminer profile image
Susiecoalminer in reply to lucretia

I have been on it for 2 years and have taken antihistamine with it 3x a day for 2 years but now the itching is getting worst.

Pandemonium profile image
Pandemonium

I cannot take Urso as I am sick within minutes of taking it. Yummy!!!

Hi Robert -- i have been on Urso Forte, and gained weight, and had more tummy issues --- Now i am on actigal/ursodial, and had lost some pounds, and tummy issues have lessened ------ plus the actigal is cheaper. -- tho still over $200 for 1 month supply for me.

Jtxx profile image
Jtxx

I have been on Urso since August 2011 and don't feel up nor down with it. Had a bit of diahorea for a couple of weeks when I started it but that settled down. My consultant reconed that because the diahorea settled down it was probably more to do with my IBS than the Urso.

Neata profile image
Neata

I have been on Urso for 10 years I have 500mg 3 times a day and don't experience any problems as also on codeine or pain relief

EAJSWW profile image
EAJSWW

I take 1500mg spread ut over 3 times a day.

It has the said effect on my gastro tract.... lovely!

Lori3161 profile image
Lori3161

The Urso has definitely made my aches and pains worse, and I have a rash on my forehead that seems to be new since taking it. At first the Urso seemed to cause GI upset upon taking it, but, that has seemed to subside. For the time being my itching seems to be under control....

Started on the capsules - I had a delayed reaction with hives after about 4 months. Now take tablets and no problems at all. Blood counts were all down except bilirubin... More bloods this week so hope it continues.

L

Tj2929783 profile image
Tj2929783

I take 250mg x4 URSO tablets in the morning. My side effects are dizziness for the first couple of hours (to the point that I have to lay down) and then slight lightheadedness throughout the rest of the day. Another side effect is gurgling stomach for the day. Also occasionally little bit of nausea, but this is tolerable. I had tried to spread out the dosage throughout the day, but this just made me feel terrible for the whole day. I find it better to take all at once and just be out of commission for a couple of hours.

Juamcc profile image
Juamcc

I have never had a problem with ursodiol except the cost.