Help B12 levels after loading dose and follow up treatment

[GJOW]

In Nov 18 I presented to my GP, anxiety, extreme tiredness, pins and needles in hands, extremely cold, ibs, headaches, brain fog. My blood tests revealed

B12 levels were 149 ng/l

Folate 2.7 ug/l

Vitamin D 43

My GP eventually agreed to a booster course of injections(5) the last one being on the 10th December and I was prescribed with 5mg folic daily til Jan. I have previously been tested for coeliac diseases but tested negative. I mentioned the instrinic factor test and was sent for this after the loading doses. This proved negative.

I have continuing symptoms and had a recent blood test on 23rd Jan 19 (some 6 weeks after the last loading dose) see above photo for results.

B12 levels were 511ng/l increased from previous test

Folate 6.6 ug/l increased from previous test

Vitamin D 39 Decreased from previous test

I have been prescribed Vitamin D tablets.

In relation to the B12 I have been told that as they cannot say whether it is a malabsorption (because of the neg result from instrinic factor) or diet related problem they will not continue with follow up injections and suggested I take a supermarket value range vitamin.

When I look at my B12 although it is now in range I would have expected it to be much higher as I had the loading doses. Do I need to pursue this further or do I assume I no longer have a B12 problem.

Looking for advice

Many thanks

[GJOW]

Thank you I am hoping this is the information you were referring to

B12 Normal range 172-910 ng/l

Folate Normal RNge>5.40 ug/l

Vitamin D Normal Range 75-150 nmo/l

I complete understand my GP does not seem interested and even said when my B12 was 144 ng/l it was not really that low.

[linkerror]

What symptoms of IBS do you have and for how long? Celiac is known to cause B12D.

[GJOW in reply to linkerror]

Hi I ve had IBS symptoms for many years but have been more since intense since approx Aug 17. I suffer from pain and cramping, diarrhea rather than constipation.

[GastritisB12]

When was your last B12 injection? I am new here too, I have been reading up like mad.

This research shows that its possible to dip below 1000ug/L 2 months after loading injections. Who knows maybe even sooner?

Much more knowledgeable posters have posted that you may need to be over 1000 to fix neurological damage.

bloodjournal.org/content/bl...

[GJOW in reply to GastritisB12]

Hi thank you so much I will have a read. Yes there is much to read like you I want to understand it more and than this will also help me to be more educated and forewarned before I return to see the GP. The last injection of the loading doses I had was on the 10th Dec so within 6 weeks it was 511 ng/l. I notice my blood test refers to ng/l not ug/l.

[GastritisB12]

Sorry you are right, my B12 test was in ng/l too. I think its a 1:1 between ng/l and the values in that study. Not 100% sure.

I hope you manage to get more injections and you get better.

[GJOW in reply to GastritisB12]

Aw thank you a steep learning curve for me. You take care too.