My mother was diagnosed as b12 deficient approx 2 years ago (I was diagnosed Dec 2016). She was never tested for PA - I tested negative but understand there are often false negatives.
My mother had 2 weeks of alternate day loading doses of hydroxycobalamin and 3 monthly thereafter. Her initial symptoms were quite severe wobbly legs and tiredness, to the extent that she could barely walk even short distances. For several weeks the GP diagnosed this as post viral even though my mother had not been unwell previously. Eventually I suggested that she ask for a blood test for b12 and reluctantly the GP agreed. The level came back at 135. Since starting the injections she has sometimes improved but at other times the injections seem to make little difference. She also always starts to feel more wobbly and tired at around 6 - 8 weeks after an injection.
Is it usual for the effect of the injections to be variable? Do wobbly, shaky legs count as neurological symptoms as if so according to NICE guidelines she should be having 2 monthly injections I believe? She has asked for more frequent injections but been denied. She is 78 but usually very active and this is impacting on her daily life and she is starting to feel very down. What can I do/suggest to help her? She also has hypothyroidism but this is under control believe. I wondered if she should push to be referred to a haematologist. I would really appreciate some advice please