Empty or full stomach isn't goingto make a difference if you have an absorption problem - think that what you have is sublinguals and idea is that they are absorbed through membranes in the mouth not in the gut
I found these took about 11 hours to start working with me, so I took them in the evening so they worked the next day. If I take them in the morning I am full of energy just before bedtime. But everyone is different. If I take sub-linguals they only take about an hour to work so I take them in the morning.
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