Symptoms alive after loading B12 inje... - Pernicious Anaemi...

Pernicious Anaemia Society

31,915 members23,044 posts

Symptoms alive after loading B12 injections.

Shivax1x1 profile image
16 Replies

Hi All. Thanks for helping me out till now earlier i had to have b12 level around 15o . But after loading injections at interval this has been reached to 550. but i have the same symptoms as they were earlier , worst thing added is i got acne and marks on my for- head and losing hair Rapidly.

when i get tested today i found my Haemoglobin higher (17.7 ) , Higher RBC(5.96),Higher Haematorcit(50.2), Higher MCHC% (35.3). does these result really indicates to gets worried about it or should i ignore?

this time i really confused what should i do because it took around 1.5 years to coverup B12 but now symptoms are not in favour and worst thing skin problem i got . Please suggest .

I am an 23 indian guy and do look like a 30-32 because my skin got ruptured. and conditions are getting worst . i used to be very handsome but not now ..

Many thanks!! :( :(

Written by
Shivax1x1 profile image
Shivax1x1
To view profiles and participate in discussions please or .
Read more about...
16 Replies
Jose651 profile image
Jose651

Hi Shivax1x1,

I understand how you feel about the cystic acne, as I believe it's called.

I never had spots of any kind growing up and to get them now is horrible.

However, this is part and parcel ( for some people) of getting the b12 injections.

They are sore and I find mine stay for about 3 weeks.

Ask your GP for some medication. I have found that 1% hydrocortisone cream helps enormously.

Be aware that you should only use very little of this cream as apparently it can thin the skin.

Talk to your GP Shivax,

Hope this helps

👍

minniemouse89 profile image
minniemouse89

Hi, I'm 26 and took the b12 injections (started the loading doses) after 3 injections, within 48 hours my face exploded with severe acne. I was told to stop taking the b12 injection and now I'm just using Skinoren (acne cream) and washing my face twice daily. I've also been prescribed anti histamines although I'm unsure how well it's going to work.

I think the loading dosage is obviously too high for you if it's causing severe acne and hair loss, but you should speak to your doctor. I don't think anything is worth going through if it gives you severe reactions/side effects.

Plus, there are always alternatives - like oral supplements at lower dosages or sublingual sprays.

I really hope it gets better for you. I know how you feel - I had clear skin, and now I look like I'm an awkward 16 year old again and even missed work for a couple of days because I was so upset and embarrassed.

Shivax1x1 profile image
Shivax1x1 in reply to minniemouse89

Thank you all for your suggestions.

Minnie, i am on the same boat like you , i feel embarrassed in talking with my office people. Really it teases a lot!!!

But my Hemoglobin , RBC count is also increasing that is also a point of concern . Isn't it?

my B12 gets high but symptoms are getting worse.

Many thanks!!

Allyson1 profile image
Allyson1 in reply to Shivax1x1

One thing that may help a little is Epsom salt footbaths for magnesium. This helped the acne for a short while, but it came back.

Allyson1 profile image
Allyson1 in reply to minniemouse89

I got cystic acne too, worse than anything I'd ever experienced. I had no warning it was from the b12 so I acted too late, now my face is ruined and my life is no longer really happy. I keep to the house mostly and don't move my face much anymore.

Allyson1 profile image
Allyson1

I would be interested to know if you have any other deficiencies? Potassium? Do you have high blood sugar? Thirsty all the time?

I couldn't diagnose anything but I had terrible acne too with b12. I don't know what caused it. My first doctor put me on high dose methylcobalamin sublinguals. The acne and other severe side effects drove me to stop the b12, and I developed nerve damage.

I was eventually diagnosed with celiac disease, bacterial overgrowth, prediabetes, and hashimotos by a different doctor. He put me on cyanocobalamin shots, and the acne was minimal, not at all cystic.

I don't know what caused the acne nor why I can tolerate b12 better now. Perhaps it is the form (methyl vs cyano)? Perhaps I've improved other deficiencies or decreased inflammation?

The acne may level out after some time on the b12, but honestly my scarring will last a lifetime so I would rather have gone lower in b12 dose personally.

I tried all sorts of creams for the acne, antibiotic cream may help.

I'm sorry I dont have specific information. Perhaps this will give you some leads.

One other thought- all b vitamins seem to cause acne. Biotin is a b vitamin taken for hair, skin, and nails. There are plenty of reviews on YouTube where women talk about biotin acne and how they deal with it.

Shivax1x1 profile image
Shivax1x1

Thanks Allyson for putting other things in my mind i was also not aware of these acne that these are because of b12 but really i came to know yesterday here on this community only from several posts that acne may occurs due to b12.

but i am really confused about my increasing Hemoglobin level.As i described earlier.

Many thanks!!

Hi

I have been getting b12 jabs for over 5 years and my MCH is still above range. I think it may be to do with Folates in my case. I don't think you mentioned folate levels but it is important to keep these balanced with b12 as they work together.

Shivax1x1 profile image
Shivax1x1 in reply to sweetnessandlight

Yes Sandy, you are correct they should be in balance but somewhere I read that if MCHC% is high then you have b12 low but as of now b12 is OK..however while typing this I feel tingling in my fingers ...

_tracy_ profile image
_tracy_

I think whether you get cystic acne may depend on the type of B12. For me, hydroxocobalamin gives me a couple of zits if I inject it or use a sublingual. If I take a methyl sublingual or inject cyano, I don't get the spots. So if you are able to switch to a different form of B12 you might be able to avoid the acne.

Shivax1x1 profile image
Shivax1x1 in reply to _tracy_

Thanks Tracy, As of now i am taking Methylcobalamin. i am not sure whether it is OK with me or not.

Allyson1 profile image
Allyson1 in reply to _tracy_

I'm the opposite...mild to no spots wit cyano., worse with hydroxo, absolute worst with methyl.

I agree switching forms is something to try

Shivax1x1 profile image
Shivax1x1

Have you got any idea if RBC is getting increased and hemoglobin also . Do these have to do anything with b12.

If it is then my B12 is 577 now then how to find correlation between both?

Dvpk24 profile image
Dvpk24

hello Shiva,

Have you found any answer for your high RBC levels?

Sagandeep profile image
Sagandeep

If b12 will increase then hb will increase, b12 along with iron and folic acid makes haemoglobin.

I’m 39 and haven’t had a breakout in decades but when I got my loading doses I got acne. It did clear up, and it gave me a great excuse to get myself a fancy face mask from Lush and have a pamper day 😊

You may also like...

Teenagers symptoms returning 4 weeks after B12 loading injections.

which started at this time but I’m now thinking it may have been B12 deficiency all this time as I...

B12 levels 6 months after loading injections

bottom of the normal range? My B12 levels have been 168, 160, 122 and now 208 over the past 2 years...

B12 loading injections but now neuro symptoms returning after 5 weeks.

a day every day. My doctor found low B12 and folate levels. B12 was 150+ I believe. I was given 5...

Worse tingling and pins and needles after starting loading dose of B12 injections

above, should I be trying to make sure I carry on with injections every two days until my symptoms...

B12 symptoms after loading doses

I had neuropathy symptoms and a B12 level just above the minimum for normal B12. (182, normal...