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How much sterile saline do I add to Methycobalamin powder?

AutoimmuneAnnie profile image
23 Replies

Hi,

I have ordered some dried Methycobalamin (from Oxford Biosciences) and sterile saline. There is 20mg of Methycobalamin in the bottle. Does anyone else purchase this dried form? and if so how much sterile saline do you add to it? What dosage do you inject?

I have previously used Hydroxycobalamin and cyanocobalamin and I injected 1ml each time.

I would be grateful for any advice on this. Thank you so much :-)

Annie

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23 Replies
Guiden profile image
Guiden

Hi the saline comes in 10ml vials just add one vial to the Methyl powder. I have just received my order and there we 20x10ml in the box, very good service only had to wait 8 days for delivery including the Easter holidays. The enclosed instructions explain what to do.

It's very easy, good luck

👍

AutoimmuneAnnie profile image
AutoimmuneAnnie in reply to Guiden

Hi Guiden,

Thank you so much for your response. I was just thinking, if there is 20 mg in the Methocobalamin, should I not put 20 mls of the saline solution, 2 vials, to make 20 ml's ? Then I would have 20 injections of 1ml each?

Sorry, I am just trying to work it all out.

Annie xx

Guiden profile image
Guiden in reply to AutoimmuneAnnie

Hi Annie, you need only put a 10ml vial into the powder, this fills the bottle containing the powder, this way, there is 1mg of methyl cobalamin for every 0.5 ml solution. If you are using an insulin syringe this would be 50units on the syringe giving you 1mg of methyl. If you want 2mgs of methyl you would draw up 100units on an insulin syringe. By using only 0.5 ml solution (1mg methyl) this gives you 20 Injections of 1 ml methyl. These are the instructions sent with the vial so I assumed this powder to be double strength. Injected myself two days ago using this method, the first thing I noticed was that the injection did not sting, totally painless . Hope this helps, it is a bit confusing as most B12 comes in 1mg dose. Please write back if you are unsure. 😃

AutoimmuneAnnie profile image
AutoimmuneAnnie in reply to Guiden

Hi Guiden,

Thank you so much for your response and help, seems a bit complicated but when I have all the bits I need I will aim to concentrate better. This brain fog is a terrible thing.

Can I ask you, how are you feeling after taking Methycobalamin?

Any better? Does it rid you of all your symptoms?

Annie

Guiden profile image
Guiden in reply to AutoimmuneAnnie

Hi Annie, I injected myself on Monday, yesterday I certainly noticed an improvement in my mood, and back pain, My memory seems better too, I'm not sure how long this will last. I also top up with sublingual Methyl this certainly seems to help. 👍

Rene7644 profile image
Rene7644 in reply to Guiden

Hi Guiden I just want to say thank you I read some of your replies to Anna I’ve just started using B12 and you have help me by explaining how to mix the saline with the B12 I’m going to do it tonight and I’m really grateful thank you for your help

Katiemelissa profile image
Katiemelissa in reply to Guiden

Hi Guiden

I have also bought some dried Methycobalamin (from Oxford Biosciences) which I have had for a while now. I usually self-inject methylcobalamin that come 'ready-mixed' so to speak, however I ordered this in case I 'ran out' of my normal methyl. The problem I am having is trying to source some injectable saline. The only saline I can find is for cleaning eyes/wounds etc which I have read is not appropriate. Can you tell me where you got your saline from please? Sorry to ask but I am going crazy trying to source the stuff.

AutoimmuneAnnie profile image
AutoimmuneAnnie in reply to Katiemelissa

Hi, I asked the same question yesterday and was recommended to buy sterile saline from here exchangesupplies.org/shopdi...

I bought some yesterday and waiting for it to be delivered. I hope it is ok. Good Luck

Katiemelissa profile image
Katiemelissa in reply to AutoimmuneAnnie

Thanks Annie,

I have just ordered it, so like you I will be waiting with anticipation...I am getting it as a back-up really for when my regular supply runs out.

Thanks again, best wishes.

AutoimmuneAnnie profile image
AutoimmuneAnnie in reply to Katiemelissa

Oooh! interesting, who do you usually buy Methycobalamin from? I could only find that source when I searched.

Annie

Katiemelissa profile image
Katiemelissa in reply to AutoimmuneAnnie

I used to get it from a lovely Doctor called Dr Riar who unfortunately passed away late last year. He gave me a couple of methylcobalamin infusions which were fantastic! Within the hour they made such a BIG difference to my health. That was approx 6-7 years ago and I haven't looked back. However I am now back to square one, looking for another lovely doctor...

Best wishes

AutoimmuneAnnie profile image
AutoimmuneAnnie in reply to Katiemelissa

I may be able to help you there :-) PM me if interested.

Guiden profile image
Guiden in reply to Katiemelissa

Hello, if you go onto the Oxford biosciences site, click on vit b12 , click on resources, scroll down to the bottom of the page to supplies until you see " 10ml sterile saline for injection: NaC1 0,9% miniplasco connect 10x10ml" click on this which will take you to Bodfeld Apothek site which is written in German. When on supplies page click on the English flag top right hand corner this will now translate into English, now scroll down the left hand side of the screen all in green, until you see Injectable solution (saline). Click on it scroll down the page it's the third item down. It's in a white box , if you enlarge it on the screen you can read what it says. Hope I have remembered this in the right sequence. When my saline arrived this week There were 20 x 10ml in the box excellent value. Good luck write back if you are unsure.😀

Katiemelissa profile image
Katiemelissa in reply to Guiden

Thanks Guiden, that is excellent. If you have found it easy to order then I will give it a go. I now have a couple of options to obtain saline. Thanks again!

Dirtyoltown profile image
Dirtyoltown in reply to Katiemelissa

Hi, I'm looking into buying some Methycobalamin ( Oxford Biosciences) as I live in London. But can I ask where you buy the liquid form (ready mixed ) please? Thanks, Cathy

honeybunni22 profile image
honeybunni22 in reply to AutoimmuneAnnie

You would have 40 injections. This is an ultra concentrated powder. The company tells you to put 10 ml saline for 2ml of B12 per .5ml solution you draw up. If you do 20 ml of saline, it means 1ml of B12 per .5ml solution you draw up.

rplay23 profile image
rplay23

Hi, Ive just ordered all require bits and bobs. Could someone advise me of how often I inject 1mg. Everyday, once a week? Thank you for any response.

fbirder profile image
fbirder in reply to rplay23

It varies from person to person. Some are happy with one every 6 months, others need them once a week, or even more frequently.

I suggest you keep a journal of your symptoms. See how long you can go without before feeling rough, then have a jab. Repeat for several cycles and you'll soon be able to figure out the required frequency.

I would also advise my doctor that I was self-injecting.

excellantz profile image
excellantz in reply to fbirder

good advice, you may notice how your body feels and gauge from that. Once I'm fully stocked with b12 again...I'll probably do a week of every day then I'll settle for every 5/6 days...I do onviously forget ontimes so it's a roundabout,

Murfie276 profile image
Murfie276

Hi, I know this post is quite old but I wondering if any of you know how long you can keep the vial for once it's been reconstituted with saline? 

I am a nurse and when we make IV medications up at work the advise is usually that it expires within a few hours....

excellantz profile image
excellantz in reply to Murfie276

oh my gosh I read you then looked at the dates, thankfully all my questions were answered by reading

Sexylegs24 profile image
Sexylegs24

How long does this mixture last before it needs to be thrown I’m tempted to buy but says 40mg in bottle doesn’t give any other information , how much to make it up to

excellantz profile image
excellantz

I also just ordered some and had similar questions, thank you all so much for your answers, all the answers are right here

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