Methylfolate works well for some people but can have unpleasant side effects for others including anxiety, palpitations, nausea, headaches, irritability. Were you advised to take methylfolate rather than folic acid?
What form of B12 are you using and are you doing intramuscular or subcutaneous injections?
I've never heard of anyone injecting methyl IM but I've googled it and it seems OK. I've never injected methyl and I'm a bit wary of it as methyl sublinguals did nothing for me at all and I've read a number of cases where methyl injections simply didn't work. I know that methyl is an active form of B12 and in theory should be better but nothing is quite that simple when treating B12 deficiency. In my opinion the best starting point is hydroxo injections as they seem to work in most cases.
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