I was ill for years with most of the classic symptoms of PA ( stomach gastritis, heart palpitations, tingling , balance issues,muscle weakness and fatigue, poor memory , irritability, hair loss, etc etc). My GP just said it was all stress and depression as my husband had been ill for a long time and life was stressful. I knew this was rubbish having always been one of life's copers! After years on omeprazole I saw a newspaper article which alerted me to the fact that it can impair B12 absorption. I asked for a test and my level was only 75!!!!!!! No wonder I felt ill. I tested positive for IF antibodies and also parietal cell antibodies and the last gastroscopy showed atrophic gastritis. I had full blown auto immune PA. I went private for an MRI scan and some neuro test and was told all was fine and offered amyltryptaline!! (Do doctors think antidepressants are a cure all! I resist taking these knowing that B12 is what I need.) After 2 years of battling I now get monthly injections of hydroxycobalamin and feel much better but my memory is still dreadful and I still get pins and needles in my hands and feet and continually drop things. Is this likely to be permanent? Has any one else had a level as low as mine? I also still need to supplement with oral sprays and under the tongue lozenges as I lead a physically active and demanding life and even monthly jabs run out. I live in fear that the NHS will reduce my injection frequency.