My drug regime daily is: 1.25mg Zelapar, 750mg Sinemet Plus and 200mg of Sinemet Plus. I have been taking 300 mg of Amantadine but it led to the blotchy skin condition Livedo Reticulasis, urination difficulties and other disagreeable side effects. Amantadine did help me to cope better with pd and stopping has necessitated increasing the amount of Sinemet I take to cope. I have looked into replacing Amantadine with Rimantadine back to 800mg ish but it is not licensed in the uk. I am concerned about the amount of levodopa I am taking esp/ecially as it causes even worse problems!