Sinemet CR and sleep: I have recently been... - Cure Parkinson's

Cure Parkinson's

25,478 members26,801 posts

Sinemet CR and sleep

Court profile image
15 Replies

I have recently been prescribed Sinemet CR to help with my sleep, or rather lack of it. I take 4 x Stalevo 100mg and 1x8mg Requip XL daily. I have been taking last Stalevo at about 7pm and Sinemet at about 10pm when going to bed as advised. I am still waking after about 2 hours. I know a lot of people have problems with sleeping and wondered if anyone had tried taking Sinemet when waking during the night? Or whether anyone has other suggestions, please.

Written by
Court profile image
Court
To view profiles and participate in discussions please or .
Read more about...
15 Replies
tlongmire profile image
tlongmire

I use Clonazapam (.50 mg). It has worked well for me.

Hugs, Terri

Jeansm profile image
Jeansm in reply to tlongmire

Me too. It has made a huge difference. No brain fog, less bumping into things, less forgetful and my husband gets a better night’s sleep too.

hi court, i too have trouble getting more than 2 to 3 hrs sleep when i go to bed . i am taking 6 sinemet plus a day plus 3 1mg requip . i tried sinemet half cr when i woke during the nite but it only worked few wks keeping me in bed till around 6am , my neuro advised me to get my meds in by midnite and take full sinemet cr then im on this 2 wks now and hav slept better only an odd nite woke around 3 to 4 am . oh how i hate being up at that un godly hr .fingers crossed it will last ,hope this helps x

jobby profile image
jobby

Hi this lack of sleep seems to get to most of us at some time. Like Cint im on simimet and ropinerol . 10 mg of Amitriptyline helps me.But still have the odd bad night ,hang in there.

jillannf6 profile image
jillannf6

H I SUE

SORRY U R NOT SLEEPTING

AT LEAST NOT HAVING ANY MEDS TO TAKE SHOULD NOT AFFECT MUY SLEEP PATTERN BUT I TOO AM HAVING PROBS EITHER GETTING TO SLEEP RO WAKGIN UP FOR THE TOILET WAY TOO EARLY

IE 6 AM TODAY

SO HANG ON IN THERE PLZ

LOL JILL

:-)

olpilot profile image
olpilot

Up until a couple of months ago I was sleeping fine, I took 15 mg ambien and slept all night. Then I started waking every hour, switched ti clonazapam, 1 mg and 1 mg ropinerole, no help. Dr said 2 mg ropinerole, no help. Now I'm trying 10 mg ambien, .5 mg clonazapam, and 1 mg roponerole not much better. It's now 4am, I'm wide awake, took a ropinerole for my legs with the only real benefit is I'll be able to walk better when I get up in a few minutes to have my morning coffee mixed with miralax. Doesn't help much either but gotta try something. No sleeping, no pooping, quit the deal we signed on for, huh?..........8)

cabbagecottage profile image
cabbagecottage

Amitriptyline along with the Sinemet Cr has helped my husband . he also takes 10mg

Goof55y profile image
Goof55y

Been having the same problem. I take 1 mirapexin slow release about 6am & 4 stalveo last one about 7 in the evening.But the main problem was sleep.PSD nurse proscribed half sinemet at bedtime. the next two morning after 8.30am freezing was really bad. Lack of sleep being main problem, This last week I have stopped the sinemet, take a stronger stalevo in the morning but have taken a sleeping tablet for the 1st time in my life, waking up having had a great sleep & feeling much better, took s.tablets for a week the freezing still kicks in now & again. Slept a good night last night WITH OUT a sleeping tablet . Time to see what can be done about freezing. Any ideas?

ozepook47 profile image
ozepook47

I am a retired pharmacist who suffers from PD. I use to make melatonin up for various patients with various strengths prescribed. Seemed to work well. Great success in cerebral palsy patients (syrup form). Unfortunately, no personal experience with melatonin.

Melatonin may help. Often overlooked by doctors. Only on script. Commercial sustained release tablet available in Australia. However, any compounding pharmacist can make capsules/syrup of various strengths if doctor prescribes it. Extract from Mayo Clinic below.

Melatonin

There is very limited research to date for the use of melatonin as a treatment for Parkinson's disease. Melatonin was indicated as being well tolerated, but side effects may have included skin flushing, diarrhea, abdominal cramps, somnolence during the day, scotoma lucidum, and headaches. Melatonin had no effect on signs of parkinsonism or levodopa effects. Further research of higher methodological strength is needed before a recommendation can be made in this area.

Reference:mayoclinic.com/health/melat...

JRltd profile image
JRltd in reply to ozepook47

My dr recommended 5mg-15mg Melatonin for sleep. 10 works for me.

jonroberts profile image
jonroberts

I take a full pill Sinemet 25/100 and 2 low dose Xanax at night. I wake up for pee breaks 3x but go back to sleep immediately. Wake up around 5:45 to take my 6am meds.

Court profile image
Court

Thanks to everyone for your, as usual, helpful comments. Much appreciated.

l1111irish profile image
l1111irish

I take a 200mg of Sinemet at bed time. It reduces the tremor and I am able to fall asleep. I have been able to get as much as 6 hours of sleep.

scottyt profile image
scottyt

Hash oil for 8hrs of solid sleep...

Axeltoot profile image
Axeltoot

I use ZZZ quill for years, works great. Good luck!!!

You may also like...

CR Sinemet & Sleep

my sleep is disrupted - much less deep sleep according to my sleep tracker, and feel fatigued and...

Sinemet and shakiness

Curious if anyone has ever experienced tremoring and more shakiness after you taken Sinemet? I take...

Sinemet? Too much or not enough?

I’ve been on sinemet for 14 years and my average dose has been 1, sometimes 1 1/2 pills every 3 to 4

More Sinemet, Comtan Needed At Night Than Day

Akinesia. During the day I can go 4 to 6+ hours on each 25-100 Sinemet/Comtan. During the night I...

Could Amantadine cause sleep problems?

addition to stalevo 100mg 6 times a day and resagaline. I have for the past two weeks been taking...