WHen I was diagnosed with PD, the Neuro put me on a low dose of Requip and zelapar. I noticed a change right away- like I could move, had my balance back and an overall good feeling. Six months later, because I was going through a stressful time, He added a anti depressant. I tried many of those and didn't like the way they made me feel. Had a horrible time getting off of it. OK- the neuro took me off of Zelapar because the Pharmacy flagged it saying it couldn't be taken with an antidepresant. Dr. thought that was nuts but because of my concerns took me off and put me on Azilect. I'm not sure if Azilect was the cause but I was dizzy all the time. I felt bad ALL the TIME. I'm wondering if I need to be on something like one of those. Do they really benefit you? Some days I feel my PD is progressing and was thinking would the meds halt its' progress.