Upcoming Clinical Trial Will Test Immunos... - Cure Parkinson's

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Upcoming Clinical Trial Will Test Immunosuppressant in Slowing Parkinson’s

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An upcoming clinical trial, known as the AZA-PD study, will test whether limiting the activity of the immune system through the use of an immunosuppressant can slow the progression of Parkinson’s disease.

The Phase 2 trial (ISRCTN14616801) — officially Azathioprine immunosuppression and disease modification in Parkinson’s disease — is a proof of concept study expected to enroll 60 patients with an elevated risk of disease progression. The participants will be randomly divided into two groups, with one set given a placebo and the other treated with an “old drug” called azathioprine

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en.wikipedia.org/wiki/Azath...

"Common side effects include bone-marrow suppression and vomiting.[2] Bone-marrow suppression is especially common in people with a genetic deficiency of the enzyme thiopurine S-methyltransferase.[2] Other serious risk factors include an increased risk of certain cancers.[2]"

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