Melatonin supplementation and the effects in Parkinson's disease

[Farooqji]

Highlights

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This study evaluated the effects of melatonin on PD.

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Melatonin improved some clinical symptom in PD.

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Melatonin decreased hs-CRP, insulin and HOMA-IR, and elevated TAC in patient with PD.

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Melatonin down-regulated TNF-α, PPAR-γ and LDLR in patients with PD.

sciencedirect.com/science/a...

[HugoRipanykhazov]

Any idea what the idea of melatonin is? Is it supposed to put you to sleep? That's what I use it for, - if I wake at night early enough to think that I might not get back to sleep again.

But with this coronoaryvirus thing, apparently Melatonin is one of the wonder drugs (lol) everyone is talking about

[chartist in reply to HugoRipanykhazov]

HugoRipanykhazov,

Here is a link to a thread on this forum about what melatonin does in Covid-19 as well as a doctor who is using it successfully in his Covid-19 patients. I update it regularly.

healthunlocked.com/parkinso...

Art

[HugoRipanykhazov in reply to chartist]

Yes, I had seen that andother similar postings. Which is why I asked what a drug produced internally by the body to put the host to sleep is supposed to do with corona virus or PD patients. Is it supposed to put the patient to sleep?

[chartist in reply to HugoRipanykhazov]

It can help a person to get to sleep, but in terms of Covid-19, when used at high dose as Dr. Neel is using in his patients, it has many positive effects that can help to ameliorate the multiple negative effects of the disease and apparently prevent or lessen the chance for the cytokine storm and pneumonia. Dr. Neel reports patient improvement in 24 hours after the first dose and none of his patients have gotten the cytokine storm or pneumonia which means no need for a ventilator and these are three things about covid-19 that have resulted in death in some patients.

Art

[HugoRipanykhazov in reply to chartist]

Thanks Art, I didnt understand that it is used to treat patients who are in desperate condition, and therefore, it doesnt matter that the main/side effect is sleep

[chartist in reply to HugoRipanykhazov]

HugoRipanykhazov,

Yes and now scientists understand that getting enough sleep can improve the immune response, so melatonin may help in that sense along with its Covid-19 specific effects.

Art