Continuous / Extended Release

[Joynb]

I used to take Sinemet CR 50/250 overnight (as well as various daytime medications. Worked well for me. Sinemet CR 50/250 is no longer manufactured. I was offered a generic product, same carbidopa levodopa mix, but extended release rather than continuous release. I have been using this for about 6 weeks. I am now really struggling late afternoon, with lots of off time.

Is anyone using this generic product? How are you going?

Do I blame the generic or do I just need a higher level of daytime medication?

[park_bear]

The generic works okay for me.

[DianeF]

I had nothing but trouble with a change in generic extended release c/l (made by my health insurance company without notice).Nausea, headaches, tremors, etc. for 4 months. My neuro switched me to Rytary and I’m back to doing well.