B12 May Slow Progression and Maintain Cognitive Function

[jimcaster]

I have posted this before, but it may be useful for those of you who are newly diagnosed or new to this site. Vitamin B12 is one of many Vitamin B supplements which may slow the progression of Parkinson's Disease.

parkinsonsnewstoday.com/201...

[geddy]

For B12 pills to be effective you need to let it melt under the tongue vs swallowing the whole pill

[WinnieThePoo in reply to geddy]

I take a vitamin complex supplement. I swallow it. The b12 is effectively absorbed without going under my tongue, as my blood tests demonstrate

[geddy in reply to WinnieThePoo]

Sublingual B12 was designed as an alternative to injections because of how poorly it is absorbed in the stomach

[Kia17 in reply to geddy]

You are right geddy. B12 Lozenges is the best form of this vitamin specially if it is a combination of Vitamin B12 (80% as methylcobalamin and 20% as adenosylcobalamin).

[Despe in reply to Kia17]

amazon.com/Designs-Health-T...

This is what my husband takes, Kia

[Kia17 in reply to Despe]

Despe

Looks good . Did you speak with your husband’s doctor about the B12 dosage?

[Despe in reply to Kia17]

I believe I did, . She didn't comment if I remember well. Anyway, it's time for a consult and more tests. Have a Very Happy and Healthy New Year!

[Kia17 in reply to Despe]

Likewise Have A Very Happy and Healthy New Year!

[Leylaleyla in reply to WinnieThePoo]

Which vitamin complex do you take?

[WinnieThePoo in reply to Leylaleyla]

Jigsaw health - Activated Vitamin B w/SRT

[Leylaleyla in reply to WinnieThePoo]

Thanks!

[Leylaleyla in reply to WinnieThePoo]

Any issue with the B6 interfering with CL?

My mom takes her CL every 2 hrs.

[WinnieThePoo in reply to Leylaleyla]

At the moment I don't take C/L although that may change on 8th (at least I may get a prescription for it, even if I hold off starting until after 6th Feb - YR2 of SPARK)

Parkbear is your man for this - I think the advice is a gap between taking the vitamins and the C/L although with a sustained release, that may be less of an issue

[jimcaster in reply to geddy]

I have been swallowing B multivitamins which are especially high in B12 and my blood tests (like Winnie's) show that it is being well absorbed. Homocysteine levels decreased significantly. There may be conflicting studies, but here's an article suggesting that sublingual forms offer no particular benefit. It's frustrating that so much research is contradictory.

healthyeating.sfgate.com/ad...

[LAJ12345 in reply to jimcaster]

I suspect people’s different genetics affect how well it is assimilated.

[Leylaleyla in reply to jimcaster]

Which vitamin complex do you take?

[jimcaster in reply to Leylaleyla]

Apex Super Methyl. Here's a link:

apexenergetics.com/super-me...

[Leylaleyla in reply to jimcaster]

Thanks!

[jimcaster in reply to Leylaleyla]

I don't think you can buy it directly from Apex. I buy mine from my chiropractor.

[Kia17]

Capsules also get absorbed through GI tract but not as much as the lozenges do . Compared to commonly used tablets, capsules and other oral dosage forms, sublingual absorption is generally much faster and more efficient. ... Peak blood levels of most products administered sublingually are achieved within 10‐15 minutes, which is generally much faster than when those same drugs are ingested orally. Absorption is very quick, and higher drug levels are achieved in the bloodstream by sublingual routes than by oral routes because the sublingual route avoids first-pass metabolism by the liver.

When a chemical comes in contact with the mucous membrane beneath the tongue, it is absorbed. Because the connective tissue beneath the epithelium contains a profusion of capillaries, the substance then diffuses into them and enters the venous circulation.

[pvw2]

Uncooked almonds are a good source of B12.

[WinnieThePoo]

The research conclusion was that a deficiency of B12 was an indicator for faster progression. Rectifying that deficiency slowed progression. Vit B blood levels do not depend on rapid absorption. The key was to restore vitamin b12 levels to the top end of the normal range. It didn't matter whether you used sublingual B12, regular B12 capsules, vitamin B complex tablets, or, as in the research itself a multi-vitamin supplement. That said, it is generally accepted that B vitamins work in complementary fashion and there is merit in ensuring adequate levels of all of them. My last test was 560ng/ml - well above 200

[PDGal4]

Thanks for posting this. I've shared this before but when I was first diagnosed 7.5 years ago, I was extremely fatigued. A wonderful MD who I was seeing for acupuncture suggested I might have a B12 deficiency and tested for it. I was borderline low and prescribed monthly B-12 injections plus oral supplements. She said either chewable or sublingual as pills/capsules you swallow whole are not fully absorbed. I had shots for 2-3 years; now I take 2000 mcg orally per day. Have my B-12 levels checked every year. This year I am going to ask to have my homocysteine level checked too from all who have shared here. Also good to know that the B-12 is not only improving energy but may be disease modifying.

[Gioc]

Jim but how do they attribute everything to b12 if they use a multi vitamin that will certainly contain b1 in addition to everything else? so I understand.

[jimcaster in reply to Gioc]

My multivitamin only has B6 and B12. As soon as I started taking it, I felt better. I am separately taking Solgar Thiamine HCl (1.5 grams daily) and 1050 mg of B3 (TruNiagen).

[Gioc in reply to jimcaster]

thanks jim I will buy a similar one and I will try it at the indicated doses.