Using natural carbidopa with mucuna

[billyroca]

Has anyone experience of this?

We tried a protocol of vit c plus several other nutritional supplements which was supposed to mimic carbidopa, but for my husband there wasn't any difference in how long the mucuna lasted.

We, ve been using mucuna for 2+yrs, but now we, re taking large amounts of it, and it, s only lasting 2hrs max.

We're thinking of combining it with prescription carbidopa, something like entacapone (we, re in the UK), but wanted a last attempt at diy PD treatments, as have worked well for quite a while.

Advice from anyone with experience of using mucuna would be appreciated.

[bassofspades]

Try egcg which is extracted from green tea, or just try green tea itself.

[billyroca in reply to bassofspades]

do you just take it at same time as mucuna?

[bassofspades in reply to billyroca]

I did.

[AmyLindy in reply to bassofspades]

What’s your Fav Mucuna source? Per chance- Is it grown/made in the 🇺🇸?

[bassofspades in reply to AmyLindy]

Honestly whatever is cheapest! I used Source Naturals brand.

[Tryguy]

What kind of amounts were working without using an inhibitor?

[billyroca in reply to Tryguy]

see reply to jeeves 19. It's stopped lasting as long as it used to, as compared to a year ago (started taking it 2 years ago)

[jeeves19]

What’s your % Mucuna?

[billyroca in reply to jeeves19]

taking 1g of 98% L-dopa from nutrivita... used to be three times a day

(although that was with quite alot of down time, i.e. not being able to function well)

no it's 1g about 8 times a day, which is far too much really...

we'll probably try the green tea on it's own. We tried it before, but maybe we didn't work out how silvestrovs protocol really worked...

my husband is dx 6yrs now and can't really function when not medicated.

[jeeves19 in reply to billyroca]

Gosh. I only take 65 mg!

[billyroca in reply to jeeves19]

I guess everyone's different! which mucuna do you take, I mean who's your supplier?

[jeeves19 in reply to billyroca]

Blackburn Distributions

[AmyLindy in reply to billyroca]

What’s your Fav Mucuna source? Per chance- Is it grown/made in the 🇺🇸?

[mgregor6 in reply to billyroca]

"my husband is dx 6yrs now and can't really function when not medicated." Yikes!

[Parkie- in reply to mgregor6]

Diagnosed in Aug 2017 at age 55. Cant fonction without help from my husband, on or off meds...

[tarz]

I've been experimenting with using the natural powdered mucuna for my source of Ldopa, combined with the natural powdered matcha green tea for my source of Cdopa equivalent inhibitor for about ten months. After trying various amounts, I have found that a teaspoon of matcha, combined with a tablespoon of mucuna seems to work best for me.

You can read about this approach at -

mdsabstracts.org/abstract/t...

The way I use it is by dissolving the powders in a cup of very hot (not boiling) water, then adding a sweetener, and a non-dairy creamer, to taste.

I drink this when I am ready to go to sleep, and when I begin to feel its effect, I go to bed, and I get several hours of good sleep.

[billyroca in reply to tarz]

Thank you for this we'll give it a try.

[AmyLindy in reply to tarz]

What’s your Fav Mucuna source? Per chance- Is it grown/made in the 🇺🇸?

[tarz in reply to AmyLindy]

znaturalfoods.com/mucuna-pr...

[reedboat2]

I take green tea with Mucuna in the mornings. I find it aids absorption. At night Ive been experimenting with grapefruit juice, small dosage, one ounce 15-30 minutes prior to Mucuna dose. It seems to help.

[billyroca in reply to reedboat2]

so the grapefruit contains some kind of enzyme mimicking the COMT inhibitor??

[reedboat2 in reply to billyroca]

GJ inhibits a different enzyme called CYP3A4. Wriga on this forum has done some excellent research on this and posted results. Check it out.

[AmyLindy in reply to reedboat2]

What’s your Fav Mucuna source? Per chance- Is it grown/made in the 🇺🇸?

[reedboat2 in reply to AmyLindy]

Amy right now I’m using Barlowe’s 40% (white) and an organic product by Weyland which is probably between 5-10%. Both are processed in the US but I imagine the source material for both comes from India like most MP.

I like the Wayland a lot and use it together with the much stronger Barlowes extract with the belief that the full spectrum might help with absorption.

I’m primarily using Barlowe’s in bulk powder, 1/8 tsp = 165mg L-Dopa equivalent.

I’m also experimenting with grapefruit juice, small dose, 30ml (about 1 shot glass) prior to MP dosing. Results are indeterminate but it’s something to try.

Anyhow I hope this helps. Happy Holidays to you and your family -

John G (reedboat2)

[715McGee in reply to reedboat2]

Hi John, thanks for the info. I find interesting your feeling to want to experiment with grapefruit juice, since grapefruit, as I have read in other comments, seems to be a barrier to the intake of lovodopa and therefore not suggested. To be verified I guess...

[danfitz]

Based on another’s post you might try adding a daily glass of grapefruit juice as well.

[Hidden]

Have you discussed your husband’s worsening situation with your neurologist?