Most of the research papers are just pieces of trash

[Farooqji]

I have been exploring the PD research for quite some time. I have found that most of these so called research papers and not just more than pieces of garbage, as these are written to strengthen the CV's of the so called researchers. It's a pity that the genuine research is not more than 1 %

[Gioc]

Hi Iqbal,

1% too good. If one examines the history of research and discovery there are not more than ten relevant discoveries that make a difference on quality of life, and they are all fortuitous discoveries. IMHO most of the researches are data recording, while what is needed is the evaluation of information, i.e. the relationship with other data .

More fundamental is the discovery, more things it explains and simplifies.

We need researchers motivated to help man with attention and strong intentions to evaluate and grasp the information that makes the difference. The history of medical research proves it.

[Rhyothemis]

Biology is not classed as a 'hard science' (e.g, physics, chemistry) - but that doesn't mean it's easy.

While I can understand frustration at the rate of progress towards a disease modifying therapy, overall, I disagree with your assessment of research on PD. Much of it is basic science research which is aimed at gaining an understanding of underlying mechanisms. It is typically impossible to predict at the outset whether a particular line of inquiry will be 'translatable' into therapies. Sometimes findings are 'spun' to make it look like as though they are directly relevant to finding a treatment, this is because, unfortunately, in our society we do not value knowledge for its own sake. I believe this may be one of those counterintuitive things - the more 'results' are emphasized, the longer it will take to get to a breakthrough.

OTOH, the clinical trials process (especially with respect to funding) needs to be overhauled - or put on a trash heap and set on fire.

[sleezy]

Some research studies are based on such a small amount of evidence that they are seemingly done to keep the researchers busy/employed. At least that's my opinion. Some research is a waste of time. That is also my personal opinion.

[ddmagee1]

It is frustrating when, seemingly, research, does not bring the results we would like to hear, for those of us, who must deal with a diagnosis, of incurable neuro-degenerative diseases of one kind, or another. Neuronal loss is not an easy ailment to fix, or to stop, and there is still much to learn about how this process begins and it's causes, and ways to prevent and/or stop the disease process, from progressing. Dealing with nonregenerative neuronal brain tissue is problematic, from a curative viewpoint. That being said, the discovery of levodopa to help Parkinson's patient's, like me, is something to be thankful for. Perhaps, more discoveries will come in the future, through research, trials, and studies, Meanwhile, we must not give up hope!

[SilentEchoes]

Amen! And don't forget the research done to bolster the agenda of big pharma and ag chemical Industries.

[ddmagee1 in reply to SilentEchoes]

The agenda to use research, deceptively, to line the pockets, financially, of big pharma, and suppliers/3rd parties, is particularly irritating to me! My wife is a diabetic and is insulin dependent. Just in the last two years, the price of her insulin has tripled. It has gone from $133.00, each prescription fill, to $400.00. This is upsetting! We are elderly, on a fixed income, have Medicare, and Supplemental Insurance. The diabetic specialist, her Doctor, Social Service Counselor all called to see if they could lower the price for her. Nothing worked! Unfortunately, many people, here in the USA, are having the same problem. It has gotten so bad, that some people have died, because they can't afford insulin!

[SilentEchoes in reply to ddmagee1]

Have you considered filling your prescriptions online and out of the country?

It's a sad state of affairs in the US, maybe when enough people take their pharmaceutical business elsewhere, they'll get the message and reform will happen.

[ddmagee1 in reply to SilentEchoes]

Yes, I did use online services for a while, but several times, shipments were delayed on needed medicines. We were thinking of Canada, but were told, we’d have to see a Canadian Doc, to write prescriptions. We are considering it.

[tarz]

I believe that the same can be said about so many so-called 'medical research papers', especially the ones regarding treatment of, and finding a cure for cancer. The AMA quacks must all be motivated by the philosophy that “the end justifies the means”, the end being the acquiring billions of dollars through phony research and treatment of the disease, and the means being the keeping of the people in the dark as to the true causes of, and cures for cancer. Open your eyes, people, and take responsibility for your own health!

[LAJ12345]

Researching and finding something doesn’t work is still a result. By eliminating things it helps hone in on the solution.

[Hidden]

You are correct . Most of the research papers are trash . They are published for adding credentials or are funded by pharma companies to further their commercial interests . ONCE THEY GO IN TO PUBLIC NO BODY BOTHERS ABOUT THE authenticity of their findings . The entire fault lies with the general public who simply go by the medical recommendations with out questioning them . Even after years of failures the public behave with herd mentality .The articles referred are only time pass for those who present or who quote .

[Hidden]

I wonder as to what these forums are doing with out standing for the rights of sufferers .

[ddmagee1 in reply to Hidden]

People who are vulnerable, because of illness, need advocacy!

[Hidden in reply to ddmagee1]

When people are vulnerable some body should take up the cause to fight on their behalf and it is a part of social responsibility .

[Gioc]

Another in English by Marco Colangeli and Dr. C. on the story of his discovery.

Thanks to Art for pointing it out yesterday.

youtu.be/uzZ1a8rnVy8(Not working as expected?)

[ddmagee1]

I agree with that!