Amantadine

[Connie18]

Is anyone on amantadine and has it helped and how. Has it reduced need form as much Sinemet ?

[Juliegrace]

I take amantadine with Sinemet twice daily. It's supposed to help with dyskinesia, but I'm not sure it's made a difference. It did not allow me to reduce Sinemet. Are you suffering from dyskinesia?

[Connie18 in reply to Juliegrace]

Yes when I am kicking in and kicking out not at peak

[Juliegrace in reply to Connie18]

How much are you taking and when?

[Connie18 in reply to Juliegrace]

Twice a day. First thing in morning and 2pm

[Juliegrace in reply to Connie18]

Are you taking the CR version? You might discuss with your dr. adding in some IR or if you’re taking IR maybe moving your doses closer together and taking more doses to avoid the wearing off.

[Connie18 in reply to Juliegrace]

tried every combination nothing stops the offs and the side effects.

[TazmanianDevil in reply to Connie18]

Twice a day means you need to take it every 12 hours

[TazmanianDevil in reply to Juliegrace]

I take it also but not to reduce sinemet. My neuro prescribed it when I told him my right foot wanted to curl up. It helped for a while but its come back but not as the first time

[Taddyb]

My husband was on Amatadine. He had to stop it because he started to have one of the side effects--urinary system issues. It's a good practice to understand the side effects when you start a new drug so you know what to look for. Don't tolerate bad side effects.

[interpreters]

Hi there!

Amantadine gave me Pancreatitis and rushed to the ER. My goal is to take as few pills as possible since the cure is not found in ANY of them. For reduced dyskinesia I take Sinemet (Carbidopa, Levodopa)with Entacapone. 25mg/100mg/200mg

[sleezy]

I had a horrible experience related to taking Amantadine. I had hallucinations and lost my balance. I ended up in the hospital. I blame the Amantadine.

[Kattripp]

Everyone is so different, and so can be their responses to the same drug.

My husband had painful rigidity while on c/l 25/100 three times a day.

Adding Amantadine twice a day changed all that, and made his c/l work better and quicker.

Since adding High Dose Thiamine 2 grams a day in divided dose, his meds kick in even faster and all his PD symptoms have improved! God bless Dr Costantini!

[Fallenirish in reply to Kattripp]

Hi, I too take C/L 4 times a day with HDT 2 times per day. My neurologist suggested that I not try 2 new meds at once do I choose to start the HDT. It surely has helped - it seems to make the C/L work better. Now I have started the amantadine - this is just the 2ond day so it remains to be seen how it will affect me

[ion_ion in reply to Fallenirish]

Hi! How amantadine works for you?

[Jzucki2]

I’m on 2 to 3 100mg amantadine. I’ve been on it for 2 and half years. I take no other PD meds other than 2g of B1. I can stay focused for 3-4 hrs in the mornings. There still left side tremors. I’v not noticed any side effects.

[aspergerian]

See ncbi.nlm.nih.gov/pubmed/221...

Search for locus coeruleus on this list. A harmful untruth is that PD is only about dopamine.

[ParlePark]

I take 2 Amantadine a day primarily for tremors. No other meds. I take 1 gr a day of B1 plus an assortment of other supplements. Still have tremors however reduced considerably from Amantadine. No other side effects except maybe insomnia which could either be a side effect of Amantadine or PD?

[Ep0522 in reply to ParlePark]

Definitely amantadine caused worse insomnia for me. Had to reduce from two a day to once a day because it kept me up all night.still have fragmented sleep, but not as bad.

[ParlePark in reply to Ep0522]

I'm on 2 (amantadine) a day. Cut dose of vit D from 5,000 ot 2,000 IU and sleep has improved for past week. I know that insomnia is also a possible side effect of amantadine. Thanks for responding.