In December I wrote to tell Dr Costantini that my initial response to the thiamine, which had been so encouraging at first, had sort of gone off. The depression I'd had before had descended on me again, I felt heavy, I was moving with the old slowness again and finding it difficult to get on and exercise. And my tremor was much worse.
He responded the same day, telling me to change from 600/600mg am and pm to 400/400.I did that and at first nothing seemed to change much and I was preparing to ask if he thought I should change again.
And then my husband said, a few times, have you noticed you are not shaking? I still was, however. I thought he was just trying to encourage me. But when we had a visit from friends and they said that they noticed I was not shaking, I began testing myself. I started doing things like putting coffee in a cup and found I could do that without spilling; I could carry two cups in my right hand without spilling;I could eat with strangers without embarrassment. Those were not big things but they were depressing reminders that pd only gets worse. And, most important of all, the depression was gone. I felt energised again and hopeful. I am at last able to exercise more.
I just want to say to everyone, don't give up on Dr Costantini's protocol. It really is worth experimenting with him until you get the right dose.
And I want to thank you all for the encouragement and fellow feeling on this forum. It is so good to be sharing the problems and finding how other people cope.
And Dr Costantini and Marco told me no need to thank them again. But I can't help but say it again. Thank you, thank you for the care and compassion they show to all of us.