Tremors getting worse. Feels like a runaway train with no brakes.

[ihateparkinsons]

I take carbidopa-levodopa 25-250 mgs. 3 tabs 3 times daily and Lexapro 5mg. One tab daily. My PD tremors are getting worse. It is slowly taking my life away,at 61 years old and around 10 years since diagnosed. Any advice would be appreciated.

[tid1]

Have you tried Thiamine (B1) as prescribed by Dr. Constantini? You can research him on the internet or on this website.

He recommends 2 grams a day (1 in morning and 1 at lunchtime). He is a Dr, in Italy who has had great success treating Parkinson's patients with high doses of B1. Be sure to get water soluble B1, so excess amounts will not accumulate in your system. This is the lowest cost water soluble B1 I have found:

vitacost.com/vitacost-vitam...

They also sell it on Amazon but it is a little more expensive there.

[laglag]

Do you exercise? Try rocksteadyboxing.org. I was diagnosed 15 yrs ago at age 46 and have been doing RSB for 12 yrs & some people can barely tell I have PD. I haven't had to increase my meds in nearly 10 yrs. I'm taking 4 to 5 C/L, 2 Amantadine & 2 Azilect per day.

Keep fighting! BTW, it's non-contact boxing, we just do the training of a boxer. RSB now has 750 affliates at least one in every state in the US & in 14 other countries around the world.

[Farooqji]

ask your doctor to prescribe kemadrine for you

[GymBag]

See your Neuroligist, I take Amantidine , some people cant take it, it must be started in very small doses under Dr. Care. WORKS for me

[tid1]

Hello Again - ask your doctor to prescribe Propranolol HCL for the tremors.

[Beckey]

Well, some meds work well for some and horribly for others, but exercise helps everyone (to varying degrees). Is there a PWR! ("Power Up") class near you? Have him join it. Go along if he needs support. I go to one every Tuesday and ballet for Parkinson's every Saturday, and I take a walk every day. Rock Steady Boxing is great!

Also, I take a natural form of levadopa (Dopa Mucuna, by NOW Labs), which I get at the health food store. And I also take vitamin B1.

Good luck to you both.

[JohnPepper]

It sounds as if you are suffering from Dyskinesia, which is caused by too much levodopa in the brain. Your levodopa medication needs to be reduced so speak to your neurologist.

No medication has any effect on the the progression of Pd. The only way I know of to slow down or even reverse the progression of Pd is fast walking. You may think you would not be able to do fast walking but you may be wrong. It costs nothing to do and i works.

Read more about this on my website - reverseparkinsons.net and contact me. It costs nothing!

[sandog]

This may or may not relate to your situation, because PD really is different for everyone. I went to a neurologist in 2010 thinking that I had essential tremors in my left had, and the neuro told me that she could tell I had Parkinson's as soon as she saw me get up out of my chair in the waiting room and walk toward her. She put me on C/L 25/100 three times a day with meals and told me to double the dosage after two weeks. Since I was noticing no other symptoms, I felt that this was excessive, got a new neuro, and cut the Sinemet to three pills/day, which my new doc suggested, along with the two tabs of Selegiline/day.

I was playing bluegrass mandolin in a band and still able to play well at reasonably high tempos, so I wanted to keep meds at a minimum. I was especially concerned about dyskinesia, and could feel it's rude beginnings, i.e. curling toes, clenching teeth, and minor torso movements, so I began reducing my C/L to 1 1/2 tabs day, which still worked pretty well until 2015, when I could no longer keep up with the band on stage. Now I can play only slowly ... it's as if my muscle memory is slowly disappearing.

I'm still on a half tab of C/L three times a day, but often feel as if I'm living in molasses. If I want the molasses to be thinner because of what i'm doing that day, I take a full tab, instead of a half ... still with a meal. Most days my dosage is about two tabs/day. I really do feel like the Selegiline smooths things out, and may be important for me. I'm not generally able to discern the "on" and "off" periods that people talk about. My neuro is a motion specialist, and doesn't quarrel with my "molasses" description. I think of it as riding the edge of dyskinesia ... just below other people knowing it. If I want to be looser, the full tab seems to suffice.

I'm also just now easing into Dr.C's thiamine regimen and will report when I have something to add. Good luck to all.