Survey of medication combos that are ... - Parkinson's Movement

Parkinson's Movement

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Survey of medication combos that are working for you(Not supplements just Meds)



I am just wondering what med combos everyone is taking and does it work? How long since diagnosis? Tried and fails? Thanks everyone. I am currently on C/L 25/100 ER 3 x day and Requip 0.5 mg 3 x day. Titrating up on the requip because it made me so drowsy. I am 2 years since diagnosis but have had parkinsons for about 4-5 years.

10 Replies

3 times C/L 25/100 per day. Thiamine 1 g / day . Diagnosed 4 years ago. Fast Tremor on the R/H when stressed.

RS313 in reply to theAfrican

TY The african! I to have tremors on right hand and leg/foot.

13 years post-diagnosis:

Stalevo, 5 x 75mg

Ropinirole CR, 1 x 8mg

Rasagiline, 1 x 1mg


RS313 in reply to johntPM

Does this combination work well for you how would you say you are doing?

johntPM in reply to RS313

I'd say that I'm doing well given the length of time that I've had the disease. Motor symptoms are not bad: I can still walk 10 miles in a day; I have tremor for, perhaps two hours per day; I have no dyskinesia. Less good are the non-motor symptoms: constipation has the biggest impact on my QOL; I have poor posture, a stoop and a lean.


RS313 in reply to johntPM

Well that's very encouraging to hear I don't have many problems either constipation is starting to be one of my problems as well I have a little Annoying Tremor in right leg and right hand I have had some dyskinesias as well but not severe

Sinemet 25/100's 4 times/day. Benztropine 1/2 mil, twice per day. B1, 250 mg per day. 2 years diagnosed. Resting tremor left hand. Tremor almost completely gone. I noticed a significant improvement when I started taking B1. I'm hoping to ween myself off all meds and just take B1. I'm am going to back off the Sinemet. Going to 3 times/day. After a week, if I don't notice any change, I'll back off to 2 times/day. I would like to get off all medications. Tired of the nausea, lack of energy, lack of motivation, poor focus and concentration. When I wake up in the morning, my 1st thought is how long till I can take a nap!

RS313 in reply to boomermania

What is benztropine

Benzatropine is an anticholinergic drug used in patients to reduce extrapyramidal side effects of antipsychotic treatment. Benzatropine is also a second-line drug for the treatment of Parkinson's disease. It improves tremor, and may alleviate rigidity and bradykinesia.[1] Benzatropine is also sometimes used for the treatment of dystonia, a rare disorder that causes abnormal muscle contraction, resulting in twisting postures of limbs, trunk, or face.

6.5 years post diagnosis (per day)

Azilect (Rasagiline) 1 x 1mg

Rytary (time release C/L) 4 x 180 mg

Neupro patch 1 x 4 mg

C/L 25/100 1/2 x 3 (as needed)

Also take a number of vitamins and supplements

Left side weakness, overall slowness and stiffness (little to no tremor).

Cut back 50 mg per dose, 200 mg per day, on Rytary recently due to some dyskinesia -- helped a lot. I've been on 6 mg Neupro in the past; also cut dosage.

This combo seems to be working well for me right now; my doc stresses consistency and to stay on adjusted dosages for 3 months to determine effectiveness.

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