Trying to get my head around the different stem cell approaches

[Coling]

Sounds like stem cell therapy is getting closer although it doesnt address the question about why the disease in the first place and whats stopping it from taking over again? I would love some comments on the different approaches as taken in this article thanks news-medical.net/news/20180...

[jeffreyn]

The SoPD blog had a couple of good posts fairly recently discussing stem-cell research.

scienceofparkinsons.com/201...

scienceofparkinsons.com/201...

[tedwilli9]

I think, perhaps, because it’s environmental in more cases than not? To find disease etiology, they’d have to understand conditions under which people in the same family, exposed to the same food, air, chemicals and germs, could have 1 member get it and others be fine. Until they can expand upon why the coming epidemic of neurological diseases has environmental factors going beyond genetics and biomarkers, and might just have to do with, say, the total environment of modernity and even modern living, food production/consumption (which includes industrial chemical practices), all the way to work conditions and the pace of modern life, then I think we’re not fully addressing the issue onwards towards preventing its progression and later the disease altogether. 🤷‍♀️

[tedwilli9 in reply to tedwilli9]

As to what’s to stop it from returning: I think the main issue is how you classify Parkinson’s. If it’s closer to something like ALS, I don’t think there’s much to a cure, because even the newly created cells will just die or degenerate. So hopefully it’s not something along those lines. Still above my pay grade.

[enjoysalud in reply to tedwilli9]

It is my understanding, based on what I have read, and podcasts that I have listened to, that ALS, as PSP, CBD, MSA and several other brain diseases (called Prime of Life Brain Diseases) are NOT Parkinson related. They all produce TAU in the brain. Parkinson's produces alpha-synuclein.

I live in California, USA, and usually the first diagnosis is parsonISM (me capitalizing). Many of us don't hear the "sonism", only parkinson's. The "sonism" (again my understanding) is given because often at first it is DIFFICULT to give any other DX.

[jeffreyn]

This thread from a couple of months ago has some more information on the different approaches being taken:

healthunlocked.com/parkinso...