Folic acid dose dr Constantini - Cure Parkinson's

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Folic acid dose dr Constantini

saraoutwest profile image
25 Replies

Hi all. The good Dr replied to me within 24hrs (bless him) advising to add folic acid to my regime for anxiety I’m experiencing. He said folic acid 1cp every morning. What is cp? Must be an Italian measurement. Does anyone know? I just don’t want to bother him again

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saraoutwest
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Xenos profile image
Xenos

Hi,

"cp" means "a pill", but doesn't tell you the dose in the pill. We are back to square one...

saraoutwest profile image
saraoutwest in reply to Xenos

Oh..of course! Thanks. I’ll ask dose when I email him next week

enricomoraca profile image
enricomoraca

1 cp = 1 capsule

park_bear profile image
park_bear

You should only do this for a finite amount of time and monitor your condition to see if it results in an improvement. If it does not result in improvement you should drop it. If it does result in improvement should take only as much as you need but no more. Why? Because more than your body needs is carcinogenic. See my writing here for details:

Folate Supplementation Carcinogenic

tinyurl.com/ycdrz5lj

Despe profile image
Despe in reply to park_bear

Recommended Product

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Folate

This Crucial Vitamin Helps Your Body Remove Heavy Metals From Your Brain and Bones

Glyphosate and other heavy metals don't go away on their own, but tend to stay put, blocking vital nutrients and wreaking havoc on your bones, gut, brain, kidneys and tissues. By taking Folate 5 mg regularly, you support your body's ability to cleanse itself, and help protect your cells' DNA.

Dr. Mercola

park_bear profile image
park_bear in reply to Despe

That is a huge overdose. Excessive folate elevates the risk of breast, prostate, and colon cancer. Please read the research I cited at the link I posted above. This is a very serious matter that is well-documented.

Also, you failed to post a link to any legitimate research to substantiate the claim you have made. Moreover, glyphosate is not a heavy metal – is not a metal at all. This alone demonstrates your citation is not to be taken seriously.

Despe profile image
Despe in reply to park_bear

If you noticed I added at the bottom "Dr. Mercola" not my citation. I agree with you 5mg might be a little high, but our FM doctor prescribed also methyl folate for controlling high homocysteine levels.

PS, May I ask if your son is a medical doctor? Thanks.

park_bear profile image
park_bear in reply to Despe

FYI, your prior comment is a citation by you of the work of Doctor Mercola. Some doctors are well informed, some are not. If that was an actual verbatim quotation it puts Doctor Mercola among the ranks of the latter. Be that as it may, I get my information from primary sources - properly done studies published in medical journals, not from any secondary source.

Methyl folate is the proper remedy for controlling high homocysteine levels, but you should be careful to take only as much as you need.

Despe profile image
Despe in reply to park_bear

OK, next time I will put it in quotation marks. :) Actually, I tried to copy/paste the whole post, but it didn't. My husband follows his FUNCTIONAL MD's prescription: 800 mcg.

park_bear profile image
park_bear in reply to Despe

The carcinogenic effects of folate have been noted at only a slightly higher dose, 1 mg = 1000 mcg. Folate is all over the place - there was 800 mcg in my multivitamin +500 mcg in my B complex, +100 mcg in every packet of emergen-C. I dropped the multi-and the B complex, and found a B complex without the folate. 1 mg of folate daily elevates the risk of prostate cancer by factor of 2.6.

in reply to park_bear

When I was on methotrexate for my erythrodermic psoriasis, the doctor told me I had to take folate with it at 800 mcg/day minimum. Glad I don't need to take it anymore.

Art

in reply to park_bear

According to this study, we may be damned if we do and damned if we don't!

ncbi.nlm.nih.gov/pmc/articl...

I guess we just can't win!

Art

park_bear profile image
park_bear in reply to

Well, isn't that interesting, because the study below says the opposite.

jamanetwork.com/journals/ja...

Cancer Incidence and Mortality After Treatment With Folic Acid and Vitamin B12

Results During study treatment, median serum folate concentration increased more than 6-fold among participants given folic acid. After a median 39 months of treatment and an additional 38 months of posttrial observational follow-up, 341 participants (10.0%) who received folic acid plus vitamin B12 vs 288 participants (8.4%) who did not receive such treatment were diagnosed with cancer (hazard ratio [HR], 1.21; 95% confidence interval [CI], 1.03-1.41; P = .02). A total of 136 (4.0%) who received folic acid plus vitamin B12 vs 100 (2.9%) who did not receive such treatment died from cancer (HR, 1.38; 95% CI, 1.07-1.79; P = .01). A total of 548 patients (16.1%) who received folic acid plus vitamin B12 vs 473 (13.8%) who did not receive such treatment died from any cause (HR, 1.18; 95% CI, 1.04-1.33; P = .01). Results were mainly driven by increased lung cancer incidence in participants who received folic acid plus vitamin B12. Vitamin B6 treatment was not associated with any significant effects.

Conclusion Treatment with folic acid plus vitamin B12 was associated with increased cancer outcomes and all-cause mortality in patients with ischemic heart disease in Norway, where there is no folic acid fortification of foods.

in reply to park_bear

I'm not sure if these two studies are completely comparable. In the study I referenced, these were 366 people with confirmed first time lung cancer where they compared this group to a non-cancer control group of 366 people for serum folate levels and what they found was that serum folate levels were lower in the group with cancer. It was found that higher levels of folate in the cancer group was associated with a decreased odds ratio for cancer. No folate was given in this study.

In the study you referenced, it is actually two different studies that were combined together because they felt both groups were similar enough to do that. These were people who did not have active cancer and having cancer was actually reason to be eliminated from the study, but oddly, they accepted patients who had previously had cancer, but "had been cured" . Cancer patients who have been cured of cancer are potentially at increased risk of getting cancer again so it seems as though this group would have been a very poor choice for a study like this as it could clearly have an impact on the study outcome . Another issue is that folic acid (800 mcg) was used as opposed to folate and folic acid may be a problem because it is poorly converted to the active form, vitamin B-9 5-MTHF. Since folic acid is poorly converted it leaves excess folic acid in the system and this itself can add to the potential for developing cancer.

sciencenordic.com/increased...

healthline.com/nutrition/fo...

Add in the fact that chemotherapy itself can increase your chances of getting cancer again and I would say this study may have a couple of serious design flaws.

cancer.org/treatment/treatm...

I think a major problem is that these studies continue to use folic acid and folic acid is definitely not the same as folate! Folic acid has issues of its own and because many of these studies refer to folic acid as though it is the same as folate, only perpetuates the problem!

No matter how you look at it, it seems that better designed studies would be useful in determining how safe or unsafe folate is and at what doses. In my case, the doctor was very clear that I had to take folate with the methotrexate and if folate is really bad for us, it would be nice if doctors stopped telling us to take it because as severe as my psoriasis was, I would not want to exchange it for cancer!

Art

park_bear profile image
park_bear in reply to

There is no dispute that Methotrexate depletes the body of folic acid and therefore you need to take more of it in order to counteract this effect.

I believe I understand the reason behind the discrepancy between the studies. Folate is required for cell division. Cancer cells are hungry for it and it aids their multiplication. It also means they consume a lot of it. The average difference in folate levels between the cancer patients and the healthy controls was stat sig but numerically not very large: 20.07 nmol/l vs. 22.52 nmol/l. So it is possible the difference in folate levels was a result of excess folate consumption by the cancer cells. The study authors admit this possibility: "The serum samples for determination of folate concentration in cases were collected at the time of lung cancer diagnosis but before therapy, so it is possible that the folate level could be influenced by the presence of cancer. In this case control study we are not able to determine if folate is a marker of lung cancer diagnosis or a contributing etiologic factor."

This paper makes an illuminating point about the dual and contradictory roles of folate:

A Temporal Association between Folic Acid Fortification and an Increase in Colorectal Cancer Rates

cebp.aacrjournals.org/conte...

"Controlled studies in a variety of animal models of colon cancer have provided similar findings: in settings where there is a particularly strong underlying predisposition to colon cancer or in a setting where neoplastic tumors are already established, supplemental folic acid is protective only before neoplastic foci appear in the intestine. Once such foci are established, the more folic acid that is given, the faster microscopic foci and macroscopic tumors arise."

The full paper makes a convincing case that a rise in colorectal cancer cases was to the advent of folate enrichment.

This interventional study demonstrated a 2.6 times increase in the prostate cancer rate due to folate supplementation:

academic.oup.com/jnci/artic...

in reply to park_bear

What I don't get is why they continue to even use folic acid in these studies when they already know that the poor absorption results in increased unconverted folic acid in the circulation which is just plain bad for us as it increases in the circulation. Why not just use 5- MTHF as that avoids the harmful buildup of unconverted folic acid. The folic acid is synthetic and a problem. Even products labeled as folate may not be 5- MTHF. If it doesn't say 5- Methyltetrahydrofolate on the label, it probably isn't!

To compound the problem they continue to refer to folic acid as though it is 5- MTHF and it is not. I'm really mad that these "study artists" continue to do studies, it appears, just to stay employed on a study. It makes it much harder to find the studies that are really good in a sea of marginal studies.

park_bear, thank you for your informative posts because they make me think and rethink when I get mentally lazy! 😊😊😊

Art

Despe profile image
Despe in reply to park_bear

You are mostly referred to FOLIC ACID, the synthetic form of B9. The doctor prescribed L-Methylfolate. The bottle reads 'METHYLPRO" L-5-Methylfolate 1mg. Like Art wrote, "we may be damned if we do and damned if we don't!" Different scientific studies with different conclusions. :(

Don't know what to do. . .the doctor, at FM Cleveland Clinic, wants my husband protected from high homocysteine levels. For the record, no cancer history in my family.

park_bear profile image
park_bear in reply to Despe

The methylfolate is the superior form, and it is appropriate to get his homocysteine level down if indeed it is elevated. The homocysteine needs to be tracked with his bloodwork, and take only as much methylfolate as is needed.

Despe profile image
Despe in reply to park_bear

You're right. Test scheduled for Tuesday, depending on the results, we'll either continue or stop. He is complaining that he takes too many "pill," aka vitamins as is. :)

JANVAN profile image
JANVAN in reply to park_bear

so Park_Bear, I look again your posts on this very bad day for me >>> stiffness the whole right site, starting at noon ? An extra pill of Sinemet, doesn't helped a lot........

of course I was taking two days the detoxifiing stuff (MSM, DMSA and Irminix) but

still......

It has been weeks (even months) that I got the injection with 5-MTHF 500 microgram ampullae.

That dosis is o.k., wenn I get it once a week. ??

Sowieso, tomorrow the blood result >>> are the references of the classic, conventional medicine o.k. ??

park_bear profile image
park_bear in reply to JANVAN

Nothing wrong with an occasional dose of 500 µg.

JANVAN profile image
JANVAN in reply to park_bear

Thank you for the quick answer....

What about Mg, citrat, citramat, orotat,.......

which form the best , and preferable pulver or capsule ??

And the dosis ??

(in these matters >>> are the videos of Dr. Erik Berg useful ?)

park_bear profile image
park_bear in reply to JANVAN

Sorry I am not an expert on magnesium.

ion_ion profile image
ion_ion

I added folic acid and almost killed me with high pressure. I stopped it right away. I never had any BP issues.

JANVAN profile image
JANVAN

I take once a week an injection with 5-MTHF 500 micrograms on advice of my doctor....,and I'm doing "well" with that : the day of the injections a bit more energie,

that's all.....

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