Let me start by saying I really, really, hope that Thiamine does all it is claimed to do.
My credentials for giving an opinion are, I qualified in medicine 60 years ago, so I saw what dopamine could do when it was first introduced. Secondly I was diagnosed with Parkinson’s a year ago at age 83, so I have a vested interest in any cure, or improvement.
Any condition which has symptoms varying day to day, week to week, or hour to hour, will have sufferers, anxious for help, trying anything they think might improve their condition. Placebo effect, wishful thinking or coincidence will have people convinced that they are improving, and some become advocates for whatever it is that seems to have helped them,
While I really hope that Thiamine helps, I would warn that it has all the stigma of yet another mass delusion. There is a major advocate, Dr. Constantine , who seems an honorable man, and I am sure is a true believer, but a fervent belief is not proof. Then there are a host of true believers who promote the cause.
One warning is that, for those who visit, or who write for advice, after carefully considering their symptoms, and sometimes examination, all get the same advice and treatment . Injections of Thiamine, so there is little need to contact him, the advice is always the same. There is one cure for whatever ails you. At least Thiamine is safe and relatively non-toxic.
I have seen many examples of mass delusion in my years of practice. Remember the recent “cure” for MS? People were flying to foreign countries to have cerebral vein blockages removed at enormous expense? Many convinced themselves that they were cured or improved, but it took years to show there was no change.
Similarly, on this website there are many pushing “Supplements” which they are convinced help them. Some taking 30 a day? These people are no doubt genuine, and sincere, but can be very misleading, and provide false hope.
I take my advice from one Neurologist, and take one drug (Proplopa) and no supplements at all. I prefer a drug with known proven efficacy, and known side effects to the possibly false hope of unknown efficancy and unknown side effects.
Some patients have a very mild form of Parkinson’s, and are genuinely convinced that their regime is the answer. I wish them luck, but ones personal experience has proved very misleading in the past.
Let me end by repeating , I really hope that Thiamine does all it is claimed to do, but I have my doubts.