I sense that I can feel blood vessels in or near my scalp changing as I head towards off-time and as the next dose as Sinemet CR (50-200) levodopa is transformed into dopamine inside my noggin.
Effects of Levodopa on Regional Cerebral Metabolism and Blood Flow.
Ji Hyun Ko, Renata P. Lerner, and David Eidelberg.
Mov Disord. 2015 Jan; 30(1): 54–63.