Mucuna pruriens and vomiting

[Parkie-]

I started mucuna pruriens 100 p. cent pure powder by NutriVita a few days ago.

1/8 of a teaspoon after breakfast, lunch and dinner. Due to nausea and vomiting, I reduced to twice a day with same result.

I dilute it in a bit of cold water and I take tea extract plus krill oil with it in the AM.

Any advise to stop nausea and vomiting? Will this go away after a while?

[hercules957]

The Hinz amino acid treatment using Mucuna claims to control nausea with 5-HTP, a precursor to serotonin. Taking Mucuna with food slows down the absorbtion and can help with nausea. Starting with small doses and building up tolerance also works for some. Then there is the mental effort to control the vomit impulse with brain power telling yourself that there nothing toxic in your stomach and overriding the nausea signal.

[Parkie- in reply to hercules957]

Hello Hercules957. Thank you for your reply. I had red about 5-HTP and had decided against it:

bebrainfit.com/5-htp-benefi...

While 5-HTP is boosting serotonin, it happens at the expense of other neurotransmitters, specifically DOPAMINE...

Reported side effects of 5-HTP are significant.

Physical effects include heartburn, heart palpitations, headache, stomach pain, NAUSEA, VOMITING, diarrhea, drowsiness, sexual problems, and muscle problems.

However, I took your advise on taking Mucuna with food today and it helped quite a bit. So thank you Hercules.

[Skydome]

Ginger is said to help with nausea. How about sipping ginger tea or chewing on pickled ginger slices such as the ones served with Sushi? Wish you better soon.

[Farooqji in reply to Skydome]

I agree . taking ginger powder is easy

[Parkie- in reply to Farooqji]

Thank you Iqgaliqgal. Yes, ginger helped today.

[Parkie- in reply to Skydome]

Hi Skydome. Thank you for your suggestion. I took ginger tea today and it did help!

[Skydome in reply to Parkie-]

👌

[Juliegrace]

healthunlocked.com/parkinso...

A thread from last year that might be helpful.

[Parkie- in reply to Juliegrace]

Thank you Juliegrace.

[movinngroovin]

Me too! I couldn't take it! I took Hinz-expensive stuff!

[Harleybob08]

With 100% ldopa you need to be accurate. Throw away the spoon, and buy a jewellers scale.

There is more to Hinz’s treatment, but try this.....

Start at 0.5g, 3 times daily. Increase by .5g weekly, to a max 2.5g x 3 times. Do NOT go beyond this.

Between one and five tabs of 5HTP daily should help the nausea. Once you get it right, it should still work for increasing ldopa.

I am a total layman, but have been through the amino acid therapy, which I would recommend, but the cost is a factor, so I hope this may help.

I also take LDN, which helps and is cheaper. This is a different solution to the problem, and should help regardless of whether you continue with the ldopa or not.

God Bless.

[Greenday in reply to Harleybob08]

The Hinz protocol does not come with a 100% levodopa formulation; instead, it includes a Mucuna extract as "D5 Mucuna 40% Levodopa" + a bunch of amino-acids & vitamins to be taken with 5-HTP.

[Harleybob08 in reply to Greenday]

I started on D5, but when the 100% came available my doc switched me over. It works fine, but I imagine Dr. Hinz would not encourage it as he has a heavy investment in D5.

My doc.....

hope-for-parkinsons.com/

[Parkie- in reply to Harleybob08]

Hi Harleybob. Thank you for the info. Is LDN ''Naltrexone''? If so, how does this help concerning this post? (seems to be an impulse control disorder med in pd). Tks

[Skydome]

I’m afraid I’m a little confused and concerned about what I’m taking myself. Are you saying that ‘100% pure mucuna powder’ is different from ‘whole mucuna powder’, the former being 100% levodopa and not as beneficial as the latter? In that case, what is the levodopa content and formulation of the ‘whole mucuna powder’ - I guess ‘whole’ here means that the product incorporates other ingredients with additional benefits such as inhibiting nausea from levodopa? Thank you!

[park_bear in reply to Skydome]

I was wondering about this also. It appears the original poster was referring to this: nutrivitashop.com/l-dopa-10...

which indeed is 100 percent pure levodopa Greenday has referred to.

I can vouch that this indeed will cause nausea.

[Skydome in reply to park_bear]

Thank you for the photo, park-bear. I can’t read the packaging very well, but it seems to be an extracted, highly concentrated form of L-dopa, I can’t see clearly from what.

[Greenday in reply to Skydome]

I've contacted Nutrivita some time ago and they verified that their product contains 99.6% levodopa derived from mucuna pruriens. It is actually just pure levodopa.

The usual concentration of the Pure Mucuna powder is approximately 4-6 % levodopa ncbi.nlm.nih.gov/pubmed/272... . It is this concentration of levodopa that proved its efficacy in multiple human studies and the less likely one to cause side effects such as nausea. It is not just the levodopa alone that makes Mucuna such an effective alternative, but other yet-to-be-identified compounds that might act as MAO-B, COMT or decarboxylase inhibitors that make it superior to plain levodopa.

[Skydome in reply to Greenday]

Thank you, greenday, for your explanation. It’s clear to me now that ‘100% pure mucuna powder’ is not at all ‘100% L-dopa’. In fact, natural mucuna pruriens contains only approx. 3-6% L-dopa. What I’m taking is the natural powder which has an earthy brown colour with some grains of black in the mix.

[Parkie- in reply to Skydome]

Hi Skydome. I think what you are using is what I need. Do you have a link for this product?

[Skydome in reply to Parkie-]

indigo-herbs.co.uk/shop/buy...

A UK-based company.

[Parkie- in reply to Skydome]

Hi Skydome. Thank you for the link. I think I found the equivalent. I am waiting for them to reply to my questions.

[Parkie-]

Hello Greenday. Many thanks for your reply. After reading you, I almost ordered Zandopa, but I am a bit confused about it. The link you gave me states this composition which I don't quite understand : ''each 7.5gm contains processed seed powder of Mucuna Pruriens 6.52 gm, in flavored base''. So, 6.52 gm of MP in each 7.5gm of ''Zandopa 200 gm package''...? No mention of ''flavored based'' or other ingredients. Also, no mention of 3.33% levodopa, no mention that it is HP-200, to link it to this study of 60 patients. Have you noticed that this study has no author? It's the first time I see a study pubished without any authors. Anyways I will keep researching this as I just realised that Zandopa's first side effect is nausea. Tks

[MissRita in reply to Parkie-]

I believe the flavor that they are referring to is that it does have Stevia in it which is a sweetener and it’s natural. Hope this helps.

[Harleybob08]

Yes, Naltrexone. Seems it causes greatly increased production of endorphins, which empowers the natural healing process. At £20 ish per month, there is nothing to lose.

Within a couple of weeks I reduced my daily ldopa from 3.9g to 2.4g. I have a clearer head, and no side effects, only one dose per day, and it even tastes nice. I am now 6months in and hoping for further med reductions, maybe even getting to LDN only.

If I was starting out again I would try this (simple & cheap) option first. Part of our problem is the number of options.

[Parkie- in reply to Harleybob08]

This is very interesting Harleyibob. I just red lots of posts on this subject and your case seems to be the greatest success. I will certainly read some more on the web about LDN. Thank you and please keep us posted on your progress.