I was diagnosed @ 38 yrs and now I am 51 yrs. I have always been considered a very positive and ambitious person. Over the last 5 years, my decline has been rapid. I take over 24 tabs of 25-100 Ldopa. I now get very little pleasure out of anything and its not because I don't have things available to do or people that love me (8 yr and 11 yr old boys and wife). I am really fighting the biology of PD. After at least 13 years of this unforgiving disease, how does one find pleasure when all the forces are in the opposite direction?