My initial symptoms improvement (before switching to thiamin HCL) is credited to 500mg/day of benfotiamine. I must now reconsider choices. HCL is reported to be effective in one to two months from starting. I will continue with thiamin HCL for the remaining 5 weeks and after two months total if I do not see greater improvement w/ HCL, I will return to Benfotiamine.
Ref: member "sunvox" posts
Has anyone found a primary finding\study reporting that benfotiamine cross or is transported across the BBB in humans?
Is the use of benfotiamine for Alzheimer's based on improving sugar control and insulin resistancey in the periphery?
I would also like to know the answer to whether benfotiamine crosses bb. It has been suggested that Dr c thinks it does not. Studies seem to say fat soluble b1 is better absorbed than water based. But fat soluble (benfotiamine) is
Man made.,.any thoughts or info
RoyProp, As a result of your encouraging reviews, in addition to studying Dr. Constantini's reports, I have today started taking 4,000 mg of Solgar's Thiamine HCL 500 mg. I would appreciate clarification as to the following:
1. Do you take the Thiamine on an empty stomach or "preferably with a meal" per Solgar's directions?
2. Do you supplement with a complete B-complex vitamin, and if so, do you take it at the same time as the Thiamine?
I am grateful that you would take time to respond. I am not on any PD meds--though, from a clinical perspective, I most certainly should be. I prefer to explore all credible natural therapeutic interventions.
Thank you.
Break the pills in half to swallow
RoyProp: I have no problem swallowing the tablets. What led you to believe this was an issue?
My issue. They catch half way down, nearly choking to death.
My initial symptoms improvement (before switching to thiamin HCL) is credited to 500mg/day of benfotiamine. I must now reconsider choices. HCL is reported to be effective in one to two months from starting. I will continue with thiamin HCL for the remaining 5 weeks and after two months total if I do not see greater improvement w/ HCL, I will return to Benfotiamine.
Ref: member "sunvox" posts
Empty stomach.
B-Complex 2 hours before or after C/L.
You should be on C/L.
I just saw your response to my query. Thank you.
Yes, I "should be on C/L" ; however, I witnessed two acquaintances experience horrible side effects.
I'll keep you updated regarding effects of high dose Thiamine HCL.
What side effects and at what dosage?
Side effects as noted in research data germane to C/L.
hi Roy i see in a previous post that you considered switching from Bentotiamine to HCL. did you switch and if so to what effect.?i can't seem to get HCL here i Canada (out of stock everywhere) but Bento is available.
i appreciate your expert advice.
thanks
We only use thiamine hcl capsules
Thanks Roy
Hi there Roy, Just wondering, did you ever return to Benfotiamine? May I ask why or why not? Dr. C believed it does not cross the BBB but I have read that it does. ? Thank you.
Dr Costantini is right
What is the proper dosage of Vitamin B 1 (THIAMIN) daily and when should it be taken---------with food ----what dosage (how many grams or mgs per dose.
I HAVE PURCHASED from AMAZON VITAMIN B 1 SUPER POTENCY (THIAMIN 500 MG CAPSULES) How often should I take a capsule and are there any food concerns or side effects to be concerned about?
I really appreciate your posts and helpful info.
dajudge
Solgar Thiamin HCL 500mg from Amazon or special order from lifeextension.com
You will need to order several bottles to get you by for several weeks at 8 tablets a day.
With of with out food.
No concerns.
Allithiamine vs Thiamine 
Thiamine HCL 500 mg seems to be out everywhere? 
Can Too Much B1 HCL (Thiamine HCL) Cause Hypertension or Other Side Effects?
Thiamine hcl update
Thiamine Mononitrate 
