Psychosis from sinemet?

This study muddies the waters by labeling impulse control disorder (ICD*) as psychosis. Psychosis is defined as "an abnormal condition of the mind that involves a loss of contact with reality". ICD is characterized by compulsion, not loss of contact with reality. So the psychosis label is not even true for ICD. Therefore this study should not even have been published with the terminology they have used.

*They also included Dopamine dysregulation syndrome (DDS) which is a form of ICD.

Inappropriate terminology aside , this study examined the correlation between ICD and dyskinesias. It is well-known that dyskinesias are a result of levodopa type medication. However, no examination was made of whether patients were also taking dopamine agonists. Therefore no conclusion can be drawn from the study as to the association between ICD and levodopa medication usage.

Let us take a look at a study that did examine the relationship between medication and ICD, here: Impulse Control Disorders in Parkinson DiseaseA Cross-Sectional Study of 3090 Patients at jamanetwork.com/journals/ja...

“Impulse control disorders were more common in patients treated with a dopamine agonist than in patients not taking a dopamine agonist (17.1% vs 6.9%; odds ratio [OR], 2.72;… Conclusions Dopamine agonist treatment in PD is associated with 2- to 3.5-fold increased odds of having an ICD. This association represents a drug class relationship across ICDs”.

As to the relationship between ICDs and levodopa medication the study finds: “An ICD was present in 17.7% of patients taking both a dopamine agonist and levodopa, 14.0% taking a dopamine agonist without levodopa, and 7.2% taking levodopa without a dopamine agonist. On multivariate analysis, the odds of having an ICD was higher in patients treated with a dopamine agonist than in levodopa-treated patients not taking a dopamine agonist (OR, 2.60; 95% CI, 1.97-3.43; P < .001). The combination of dopamine agonist and levodopa use, compared with dopamine agonist use alone, increased the odds of having an ICD (OR, 1.42…”

I've been buying shoes that I mostly don't need and havnt even worn. I've never been a shoe person - never get the jokes about women and shoes - but now have 5 boxes sitting in my bedroom! It's odd as I know I'm acting out of character but don't really care. I don't understand myself really.

Could be worse I suppose!

Yes, I do believe I have experienced some mental peccadilloes.

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opposite sides of the spectrum

I have caused some troubles on this site seeking answers. I come by it naturally.

Cumpulsive behavior is just as prevalent as impulsive behavior

Same with obsessive and risk taking behavior

It's all under the dopamine umbrella

As is motor control

If you are having issues with motor control symptoms than ur having issues with behavioral symptoms as well

Dopamine controls all of it all the time

It’s not like sinemet only medicates a pwp’s movement

It medicates behavior as well

The problem is that nothing is wrong with a pwp behavior Aside from depression that is also a symptom of Parkinsons

So sinemet medicates too much in a way

And that causes unbalance in dopamine

Which causes issues with behavior

U don’t have to have extensive medical knowledge to figure this out

It’s just common sense

Dont try to argue with Serenity, he will always have an answer, and probably one you will not understand, its a brain thing. Happy New Year.

It is my research that the endocannabinoid ( how ever you spell it ) is the neurotransmitter that regulates the other neurotransmitters.

WORKS FOR ME

WE have so much in common with PTSD patients. Some event or condition threw our brain out of wack.