Intestinal permeability and gluten/wheat - Cure Parkinson's

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Intestinal permeability and gluten/wheat

jeeves19 profile image
15 Replies

Who originally claimed this and why do clinicians roll their eyes at me when I mention it? It seems to me that this is either a physiological fact or it isn't. If it's true why aren't doctors trained to either accept of know about it? Is this intestinal permeability scientifically proven or not? And for those that support the gluten theory, is it okay to consume bread/grains that are gluten free of is wheat generally a no-no?

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jeeves19 profile image
jeeves19
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15 Replies
Oceanwind profile image
Oceanwind

Hi Jeeves19

Yesterday I was at a conference about research going on in Parkinson's and the micro biome was discussed as an area that there is much interest in. There are so many interactions in the gut (bacteria, viruses even fungi as possibly affecting it, the role of diet and inflammation, and the permeability of the gut affecting active metabolites, hormones, neurotransmitters, vitamin production, toxin degradation ) that causal relationships are scientifically hard to prove! Does the virus/bacteria/or fungi travel from gut via vagus nerve to brain, or is it possible that some problem starts in the brain and travels into the gut? It is complex! Leaky gut was an area mentioned, and I noted to myself to do some research and perhaps alter my diet.

Blackfeather profile image
Blackfeather

I am doing the plant paradox diet which not only address gluten, but maybe more importantly deals wth reducing the amount of lectins in the diet that can cause intestinal permeability. Already can see a difference in my microphone. Check out Dr. Steven Gundry on YouTube.

jeeves19 profile image
jeeves19 in reply to Blackfeather

Your microphone?! Only kidding.

jeeves19 profile image
jeeves19 in reply to Blackfeather

Just bought the book and read much of it this morning. I was particularly distressed at the revelations that the PPI's (omeprazole etc) di so much damage. I've been on this sort of thing for years and always suspected that they were trouble BUT as usual, when I asked the GPs about coming of them they just shrugged and said 'then get constant heartburn'. I will definitely join you in this diet now. I went for Keto once and gave it 6 weeks but felt no benefits. However, I'm slowly waking up to the understanding that one needs to adopt such protocols for life possibly if there's any hope of returning back to health. If you can private message me with any ideas on what your favourite recipes are I'd welcome it!

Astra7 profile image
Astra7

Not sure how it works but gluten makes the stomach less attractive for good bacteria to thrive. My integrative GP is clear on this.

I saw her yesterday. She mentioned overnight fasting, excercise and eating preferably 1kg of veggies a day!!

aspergerian profile image
aspergerian

In Pubmed, lookup

gluten zonulin

Way to leaky gut and inflammation .

aspergerian profile image
aspergerian in reply to aspergerian

Also,

Permeability gluten

Permeabilty zonulin.

As blackfeather reminds us, wheat is not the only source of lectins.

faridaro profile image
faridaro

"Is this intestinal permeability scientifically proven or not?" - here is the answer from Josh Axe's book "Eat Dirt" - "...more than twelve hundred studies on intestinal permeability published in the last year [2015] alone".

According to the author the research was published in journals such as "Clinical Gastroenterology and Hepatology", and "Gut". This is a good book to learn about leaky gut, it explains in easy language development of intestinal permeability and it's treatment with many references, here is a small excerpt: "In 2000, Alessio Fasano, MD at the University of Maryland made a discovery.... Fasano isolated the only known physiological substance that directly controls the tight junctions in the gut wall, a substance he called "zonulin". Making this discovery has been compared with finding the root source, sometimes called the "smoking gun" of leaky gut syndrome". So, try to find studies on zonulin and show your doctors, although some may not be receptive to new information, but it's good to try. By the way, I always look for educable doctors to be my providers, who don't think they know everything and there are some of them out there.

jeeves19 profile image
jeeves19

Thanks for your comments gang. Interesting, especially the presence of zonulin which I haven't heard of before. I think what I was trying to say is that I probably believe in the leaky gut syndrome but have always wondered why my GPs (and I've had several) seem to have never heard of it. If it's 'science' why aren't they trained to understand it if it plays such a key role in so many diseases? They seem to relegate it to the world of alternative health which strikes me as unfortunate.

faridaro profile image
faridaro in reply to jeeves19

The way I see it in the US - the health industry is run by pharmaceutical companies which provide "continued education" for doctors and since there's no pill (to make money on) for the leaky gut, nobody is interested in diagnosing it, because conventional US doctors are not covered by malpractice insurance if they prescribe treatment/substance not listed in Physician Desk Reference.

Padram profile image
Padram

Hi Jeeves,

edinformatics.com/math_scie...

The section on Lectin and auto immune disease, talks about RA and lectin.

beauxreflets profile image
beauxreflets in reply to Padram

Interesting read, thank you.

Fava-1 profile image
Fava-1

Wheat has been genetically modified over the years. I don't think the few old time varieties left gave people the trouble we have today. My arthritis became really awful and eye problems came on, before going gluten free. Everything got better. Do research and follow your heart and (gut instincts) on what is best for you.

mj2dg profile image
mj2dg

I had so many stomach issues for years and the only help I got from a GI MD was to put me on a bunch of pills (Nexium 2x day, zantac 2x day, Donnatol (anti-spasmodic) 2x day, another anti-spasmodic I can't remember the name of 2x day) and I barely got relief. I finally went to a naturopathic MD and she put me on a gluten free, dairy free, anti-inflammatory diet and all my stomach problems resolved, most of my pain went away and my PD improved a bit.

You have to be careful of most of the gluten-free products in the store though because they put a lot of ingredients that are inflammatory and non-nutritious in to replace the gluten.

jeeves19 profile image
jeeves19 in reply to mj2dg

Excellent post! Thank you🙂

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