I think we all wonder how we compare to others that are on the same PD journey. I recently had to increase my dosage to control my symptoms. I cannot find another survey or graph that shows the relationship between daily dosage and disease duration. Immediately after my diagnosis, I was taking 300 mg per day. I increased to 600 mg at 2 years and am now at 800 mg at the 2.5 year mark.
How do you compare?
600, 5 years
My hubby takes 1200 mg extended release daily. Diagnosed 4 years ago.
I take 800 a day even though I was only diagnosed 8 months ago. But the beginning of my motor symptoms were in 2013. I'm the non tremor type.
980 mg (4 Rytary), diagnosed 4 1/2 years ago. I believe the dosage is as variable as the symptoms. This is a snowflake disease!
5 years 600mg but I feel like I need more
I'm not sure how you're doing your calculation, but I take four 25/100 C/L's so I'm assuming that is 400 mg per day? I also take 2 Azilect & 2 Amantadine. Diagnosed 14 yrs ago at age 46. Before I retired, I was taking 500 mg but because of getting rid of the stress from working, I was able to exercise more and therefore was able to reduce my meds.
I've been taking sinemet (along with amantidine) almost as a prn. I've been trying to get by with as little as possible since sinemet brings with it that horrible dyskinesia and this weird problem vocalizing. Maybe I'm barking up the wrong tree. I usually don't take the meds before Rock Steady Boxing, but I did today and boy was I sorry! I felt like my brain kept shorting out. I kept feeling like I was going to fall down.
Hello
Parkinson progression is so hard to ‘pin down’ because it affects each of us differently and the disease manifests itself in different ways aggressive, mild, tremor dominated etc.
I have had the disease for over eight years and I am taking 800mg of Levodopa (Madapor) each day. I only started taking it over two years ago and I would say I am at stage 2 of the disease progression.
All the best.
Lovepug
I take 900mg a day, diagnosed 2 years ago.
Dx 5 years ago. Now 1/2 Madopar (100+25) 2 times a day alternated with mucuna.
I think it's better to take low dosage as you can.
I'm taking about 500 mg a day, 25 / 100 C/L, and I just started amantadine. Twice a day, I think it's 100 mg. That seems helpful with the dyskinesia, which isn't actually bad yet but it's very irritating, especially when I'm driving. I drive a mini which is very sensitive to all my movements. I was diagnosed four and a half years ago with symptoms for about 7 years.
I was diagnosed in 2005, and have been taking Carbidopa/levodopa 25MG-250MG. I have insomnia and dyskinesia, plus poor appetite and periodic nausea, sometimes leading to vomiting.
1400, 6 years
Dx 2 years. 450 per day.
Really interesting thread seeing the wide range. The main thing I'd like dopamine to help me with is bradykenesia, mainly in my hands. I have a very little tremor in my left hand and no left arm swing but I don't care about those much, or my stiff, a little stooped posture. I'm on 300/day and have just increased to 400/day but still the only effect is nausea with my early morning pill. Nothing positive. Dr said I should play around with increasing it, but maybe I'm just someone who it doesn't help.
i was diagnosed 11 yrs ago, but was showing symptoms 4 yrs prior to that. i started out with sinemet 400 mg/day. about 4 yrs ago i increased it to 600 mg/day. currently, for the past year of so, ive been taking 800 -900 mg/day. i take half pills during the night (depending how im sleeping) to prevent dystonia of the feet during the night and first thing in the morning.
Diagnosed in 2011, symptoms started in 2008, started on 200-300mg (25/100) c/l January 1, 2013. Weaned off in July 2013 due to dyskinesia. Went back on beginning May 2015 at 200-300mg per day. I take between 300-350mg per day in 1/2 and quarter pill increments at intervals of 30, 45, 60 and 90 minutes throughout the day. I do not take any meds at night. I should be taking more but dyskinesia takes too much out of me so I under medicate.
My husband (PWP) takes 200-300 during the day + a 200 controlled release at night (otherwise he can't turn over in bed). If he takes more then the dyskinesea becomes intolerable. He was diagnosed 12 years ago. His mobility is poor as his thigh muscles seem unable to support his weight & he's had both his knee joints replaced due to osteo arthritis. The right knee replacement (on his affected Parkinson's side) has never seemed to be quite right. He also has a lot of pain in his legs caused by a crushed nerve in his spine.....but apart from that, he's great! Lol
Scheduling meals around taking Carbidopa/Levodopa medication
Ongentys this medication WORKS!
Has anybody had dyskinesia symptoms from Sinemet?
C/L induced Dsytonia - extreme pain. 
parkinson’s and high-dose B 1 therapy 
