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Anxiety and Gut Bacterial Choline Consumption

Anxiety and Gut Bacterial Choline Consumption

Metabolic, Epigenetic, and Transgenerational Effects of Gut Bacterial

Choline Consumption


•Gut bacteria compete with the host for choline, decreasing


•Microbial choline degradation depletes methyl-donor metabolites.

•Microbial choline utilization alters in utero epigenetic

programming of the brain.

•Mice with choline-consuming gut microbiota display altered behavior.

6 Replies

Have you looked at the role chronic exposure to glyphosate might play in gut dysbiosis?

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Indeed, the glyphosate papers by Samsel and Seneff seem very

important. For instance, they rely heavily on peer-reviewed

citations and also on the fact that glyphosate was patented as an

antibiotic whose effects largely arise from inhibition of the

"shikimate pathway", thereby altering the gut microbiome. Their

first paper explains the shikimate pathway (in technical language)

and presents speculations (hypotheses) that are based upon numerous,

published findings and that set forth possible links with the glut

of chronic diseases.

Samsel and Seneff's papers represent a stand against Monsanto's

version of glyphosate "science" and thus have become controversial.

Here's a link to their first paper.

Glyphosate’s Suppression of Cytochrome P450 Enzymes and Amino Acid

Biosynthesis by the Gut Microbiome: Pathways to Modern Diseases.


uuu yea. I think that's right.


Aspergerian, do you by chance know what bacteria are suspec of consuming the choline. I may be able to selectively kill them off.

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Choline research is complicated. Two links illustrate the challenges.

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thanks for the article


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