Just shut up and take your meds!

[Ianfrizell]

Hi all

My vlog about levodopa and dopamine agonists used in the treatment of Parkinson's Disease, their effects and side effects.

youtu.be/xVKXx5a-qbs(Not working as expected?)

Cheers,

Ian

[Serenity_finaly-1]

Stay STRONG Ian and thank you for your work.

[seamus60680]

Another good, well informed vlog thanks.

Perhaps a vlog on current advances/exciting research/possible cures in our lifetimes could be considered next.

[Ianfrizell in reply to seamus60680]

That's a hell of a task you just set me, but then I'm up for the challenge! Don't expect it for several weeks, though - I see a lot of research ahead.

Cheers,

Ian

[Red-or-Dead-Carol]

Thanks Ian this is great. Please tell me how did the screen you for impulse control possible problems? I ask you as I have just been prescribed One of these.

Thanks and best of luck

[Ianfrizell in reply to Red-or-Dead-Carol]

Apparently the risk factors for impulsive behaviour include: being male; having early onset PD; smoking; family history of gambling or alcohol abuse; single person living alone; personal history of addictive behaviour; mood problems including depression. I'm not sure if there are more indicators, but my neurologist certainly questioned me in detail on the above.

Cheers,

Ian

[Red-or-Dead-Carol in reply to Ianfrizell]

Thank you for your help in this, very useful information.

[aspergerian]

A very important vlog.

I can't help but wonder how patent ownership of Sinemet and dopamine agonists shapes research and constrains PD foundations.

[Ianfrizell in reply to aspergerian]

...or how the pursuit of money stifles debate about this devastating side effect.

[MBAnderson]

Thank you Ian. Another good one.

[Cbgs]

Ian

Thnk u

I look frwrd to ur posts

I just want to add a comment

It does not refute what you say

It's just added info re C/L :

This was a hot scientific debate in the 1990s and 2000s. Despite evidence that C/L can be toxic to cells in a pétri dish, there is no evidence that this applies on tissues or on living organisms (tested on animal models and by long studies in humans). There is no evidence that C/L causes cel damage or toxicity in humans with either short or term use.

Many pharmaceutical companies trying to sell the more expensive dopamine agonists used the argument that C/L is toxic to boost their sales (indirectly of course).

In sum, there is no scientific evidence that C/L is toxic to humans

Hope this helps.

Be well

Best regards

C!

[Ianfrizell in reply to Cbgs]

I understand that there is no proof - a very difficult thing to prove or disprove. Then again, we are denied medicinal cannabis on the basis that there is no proven benefit, and I KNOW that it benefits me. Despite the lack of in vivo evidence, I find the in vitro evidence sufficient to make me want to avoid these drugs for as long as I possibly can.

Your comment about pharmaceutical companies using unproven evidence to boost sales of agonists makes me despair of humankind.

Thanks for your comment!

Cheers,

Ian

[Godourtruehealer]

The big reason why the pharmaceutical companies aren't interested in finding a cure is because people are jumping to use their medicines as soon as they get a diagnosis.