Need Advise

[roncourtney]

I take Senemet, 25-100, three times a day. I understand that the 100 stands for the mg of L-dopa in the prescription. I'm trying to substitute Macuna Purins for at least one of the Senemet daily. The Macuna I have says it is 15 mg per tab. Is there a way to calculate the amount of Macuna to take? Hopefully not 6-7 tabs for one Sinemet. Also, my doctor says taking anything other than her prescription for Senemet is a waste of time. What do you guys think? I also talked to a major clinic and who said that they had never heard of any documented evidence or research that says Macuna does anything for Parkie people. Again, what do you guys think? And finally, I'm told that the carbidopa in the carbidopa-Levadopa prescription keeps the levodopa from breaking down before it has a chance to reach the blood brain barrier. They say that Macuna has nothing in it that does that and therefore is a waste of money. Any thoughts?

[Bailey_Texas]

All evidence that Macuna Purins works is anecdotal. Using Macuna Purins is risky due to the fact that there is no over site by anyone. What you are getting may contain 10% or 50 % of the substance you are looking for or could contain 0%.

[Hidden]

"...other than her prescription for Senemet is a waste of time". as it goes for Mucana, which I have tried. Other than that, try something else. Let us know if it works.

[Xenos]

Mucuna Pruriens is a bean rich in L-Dopa. But there is no way to know how much.

What if people satisfied with Mucuna Pruriens were in fact those unknowingly taking 2 to 10 times more L-Dopa than prescribed through Sinemet ?

[JohnPepper]

No Pd medication does anything to slow down the progression of Pd, which is what we should all be looking for. I am led to understand that Mucuna is a natural substance containing levodopa. But as levodopa does nothing to slow down the progression of Pd, but has serious side effects, then should you even be considering which one to take?

As you are already taking levodopa medication, did you find that some of your symptoms were better after taking it? If not, then why are you taking it? If they are, then I would suggest that you continue to take it but look at ways of slowing down or even reversing the progression of your Pd.

Look at my profile and see what I have been able to achieve in this battle against my Pd. Then make your own decision as to what you want to do. I make no money out of telling you all this, I just want you and everybody else to start doing exercise to slow down the progression of your Pd.

[trishtheteacher]

I take mucuna pruriens and sinemet. Mucuna works better and faster than sinemet, for me at least. Additionally, research I've read says that mucuna is neuroprotective.

[Harleybob08]

As far as I can tell, the LDopa in sinemet is exactly the same as the LDopa in Mucuna.

nature.com/articles/srep11078

Sinemet comes with Carbidopa. This is used to combat nausea, but has serious side effects, one of which is nausea. 5 HTP is better. As the LDopa ratio to Carbidopa and 5 HTP are different, I would not pick and mix, but stick with one or the other.

Really best to go with a doctor specialising in the Dr. Marty Hinz protocol.

[cshamb in reply to Harleybob08]

I tried the Marty Hinz treatment but could not swallow that many pills and had terrible indigestion so I had to stop. Heard that it is good but can be expensive. I am back to siminet and mucuna. I take 3 mucuna (NOW) product and 25/100 siminet, 4xday.

[Harleybob08 in reply to cshamb]

I use powder rather than pills. The doctor I use uses 98% Mucuna LDopa. This is a fraction of the price of the 40% Marty uses, and , of course far less bulky.

I pay around £20 per week for meds; although the initial contract is around £2K.

What price quality of life.

[jeeves19 in reply to Harleybob08]

Which doctor do you use?

[Harleybob08 in reply to jeeves19]

Dr. Ron Cargioli.

[e-mail]

hope-for-parkinsons.com/