I have just started taking Mucuna Pruiens and Sinement with a new prescription of Rasagiline. I have had two episodes where I have felt overly energized and a rush of energy with no Parkinson's symptoms but lasts about an hour and a half and feels as if I am on some type of speed. Has anyone taken these three together and had any problems? I've talked with my doctor and she eliminated the Mucuna until we meet in 3 days.
Having side effects from taking Mucun... - Parkinson's Movement
I had a heck of a time using their search box to find mucuna because the page would erase and change after 2-3 seconds, before I had time to enter the keyword.
Here is the specific page on their web site where they sell mucuna/kapikaccchu powder--page also contains a link for liquid extract:
I was disappointed that they made no mention of its relevance for treating PD, but, upon reflection, that makes good sense: they avoid having to include that humiliating medical disclaimer enforced by the FDA.
Azilect has been tracked in connection to adverse events as are many drugs. Death is the most serious event of course. Death has been tracked by the FDA in connection to azilect administration. Events recorded by FDA by any pharmaceutical involved can be searched.
Read Mucuna vs Parkinson's it gives a lot of advise on taking Mucuna with or without these drugs, and was written by a neurologist. For what I read, you probably had to much l-dopa in you system. Mucuna l-Dopa is just as strong as levadopa, so you need to have you neurologist adjust your dosage. The suggestion in the book is to slowly substitute. The advanced is the natural levadope has virtually no side effects. Mucuna also has a natural MOA inhibitor as well as over 40 other co-factors which are not fully understood, but it seem to amplify the effecticy of the l-Dopa. You also may want to ad green tea extract and green oat extract. I've been managing my PD with only natural supplements for a while now. I've done it under the supervision of my neurologist, and it's meant adjusting what I take until I find what works best. I'm still not sure I've found it.
I am also taking mucuna along with c/l. I just get the NOW product from the health food store and so far take 3 a day. You are lucky to have a neurologist that helps you with the dosage of mucuna. The book I read that explains mucuna is MUCUNA VERSES PARKINSON TREATMENT WITH NATURAL LEVODOPA by Dr. Rafael Gonzalez Maldonado.
Mucuna versus Parkinson. Treatment with natural levodopa by Rafael Gonzalez Maldonado (Author) you can find it on Amazon, he also has a few other books on Parkinson's see amazon.ca/s/ref=dp_byline_s...
Very important to take the "CR" - controlled release - version of Sinemet rather than the default immediate release version. With immediate release your dosage of levodopa is extremly uneven - way too much at first. The CR version gives you a nice even levodopa level for 8 hours or so - smooth as silk.
I've been taking "Now" - Dopa Mucuna for about 6 weeks now. This, alongside Ropinirole, and Azilect (rasagiline). I started this because of dyskinesias caused by Sinemet ( I know this, because as soon as I stop the Sinemet, the dyskinesias stop).
I reduced Sinemet by cutting each 125mg tablet first into 2 then into 4, so tiny pieces.
I stopped it altogether and substituted 3 x Dopa Mucuna a day instead. This wasn't enough on busy days, but quite sufficient for lazy days. If I know I am going to be active, I supplement my Mucuna with 1 or 2 tiny pieces of Sinemet, so 30mg or 60mg. This seems to make the levodopa in the Mucuna, more accessible. The downside is that the dyskinesias are more obvious.
As with all PD meds, it's a case of balancing alleviating symptoms against any side effects.
And Mucuna doesn't agree with everyone - but then neither does Sinemet!!