Coconut Oil + Trehalose? Worth a look!

Hi All,

My name is Joe Peck. I have a different disorder known as Spinocerebellar Ataxia Type 1 and have been very active in the AtaxiaUK forum where I have been working hard to share information about trehalose to wit I'd like to provide a tiny introduction here and encourage everyone to take time to research trehalose and the possibility of combining trehalose with coconut oil as a complementary therapy. As I have been strongly warned before I must add the caveat that I am not suggesting anyone try ANYTHING without first consulting with their doctor on the safety and potential benefit. All I am doing is providing reference material that one can take to their doctor to start a discussion.

Now to the links of research:

I couldn't find any scientific papers linked in the threads on coconut oil that offered any reason as to why coconut oil could be beneficial so here is a paper that summarizes the current research and provides plenty of links to the underlying scientific work which so far has only been done in animal models and not humans:

The role of dietary coconut for the prevention and treatment of Alzheimer's disease: potential mechanisms of action

cambridge.org/core/journals...

and although not for Parkinson's it is interesting to see that there is a human clinical trial of coconut oil for the treatment of Alzheimer's:

clinicaltrials.gov/ct2/show...

Next here is a thread in another US forum on my disease that covers research on trehalose:

ataxia.org/forum/toast.asp?...

Here is a paper directly correlating trehalose and Parkinson's:

ncbi.nlm.nih.gov/pubmed/?te...

And, here is a link to my latest post on trehalose in the AtaxiaUK forum wherein there is growing support among real researchers on this simple sugar:

healthunlocked.com/ataxia-u...

It looks to me as if the combination of the two might be very interesting to examine!

Joe

5 Replies

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  • That's interesting Joe. As stated a couple of weeks ago I was showing positive results taking Trehalose orally. I have not yet worked out the optimum intake for me but I have been using coconut oit in preference to oil for at least a year. I use the type that is cold pressed and have to say I also enjoy the odd raw spoonful. Maybe this be a contributing factor as to why Trehalose has been working positively for me.....?

    As I said earlier, I'm accepting that my results may well be due to Trehalose combining with something else that I take so will not be changing any of my current supplements or diet at present.

  • Is this the same as mannitol?

  • I note that an NIH/PubMed safety/human tolerance study only tested up to 50g. The amount recommended in your Ataxia forum of 75g p/day (almost 3oz) seems less than practical in order to test a hunch. Source: ncbi.nlm.nih.gov/pubmed/120...

  • I'm working now so the short answer is the one and only human trial of trehalose which translated mouse research into human benefit used 100g daily.

    The problem with trehalose is that it is beneficial only when the whole molecule gets to the brain and there is viratually no research available that shows how much humans can get to their brain through oral ingestion. I have been experimenting with spraying super saturated fluids into my nose. Also BioBlast is injecting 13.5 g or more directly via IV in order to achieve results in patients with OPMD and SCA3. Theoretically based on the human study of disaccharide permeability I linked above, 100g of trehalose might result in a mere 0.5 g of trehalose molecule actually getting into the blood stream . 97% or more of trehalose passes thru the body undigested.

    My knowledge on trehalose is extensive enough that doctors from Harvard and Cambridge are consulting me. Feel free to contact me via email directl if you want more information or proof. I am not a quack and all I want is to help as many people as I can.

  • And since you lack a "control" subject (or body-double of yourself) any perceived benefits (or adverse effects) derived from all the effort expended on the experimentation will forever remain anecdotal at best.

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