help in the bedroom

[Carolinagirl123]

Do any of you guys out there suffer from erectile dysfunction--but not all of the time? If so, has anyone had the penile implant? Any advice would be appreciated.

[Donzim]

Sexual dysfunction is a clinical sign of PD as dopamine (or lack of it) regulates that urge. People on too much dopa may well be hyper sexual but with too little, a person may well lose all interest in sex. Those who get occasional urges are probably getting them when their dopa rises. Unfortunately, too much dopa is NOT a good thing. Sorry to be the bearer of such bad news.

[Carolinagirl123 in reply to Donzim]

i am actually very happy, he is the one in our relationship who thinks it will make him and me happier. i wonder how an erectile implant really works for men with pd. i think the urologist really wants the money, and doesn't seem to concerned about the fact pd presents issues of its own. thanks for your reply.

[Donzim in reply to Carolinagirl123]

Surgery for PD patients is always very serious...not like normal people. Special care must be taken with anesthesia. The issue is frequently the actual interest in sex which is directly related to dopamine. No dopa, little if any interest. You must go online about that and consult your neurologist, hopefully he specializes in PD.

[park_bear in reply to Donzim]

I have not heard of " People on too much dopa may well be hyper sexual " - that is usually a problem caused by dopamine agonists, not levodopa.

[Donzim in reply to park_bear]

May be. I just know some raunchy PD guys who are obviously on too much of something. Maybe I just assumed that too little makes one impotent that too much may do the reverse! Whatever it is, it was a great loss to womankind in our case!

[Hikoi in reply to park_bear]

Actually any dopamine replacement therapy can cause problems PB including L/C. Sometimes it is not just one med but the cumulative effect. And being ok one year is no guarantee for the next year unfortunately, compolsive behaviour can happen at any time.

[park_bear in reply to Hikoi]

Sorry not getting the acronym PB. Be that as it may, I have yet to see tales of woe posted as to how a PD senior on levodopa lost it all due to compulsive gambling or got in trouble due to compulsive sexual conduct.

[Hikoi in reply to park_bear]

Good pont PB (Park Bear) nor have I. However have noticed warnings in med inserts and my own behaviour changed (internet addiction) with the upping of L/C

[TheGimba]

My husband suffers from erectile dysfunction. What is worse is that he doesn't seem to care, total apathy. He has no interest in me physically and hasn't in years...and I'm still hot LOL. I wish I had some advice for you. Hard to get any good advice on this topic, even from neurologists.

[Donzim in reply to TheGimba]

You are right. Directly related to dopamine.

The first doc who examined my husband with PD asked the following question right out of the box, 'Can you still get it up?' He was so embarrassed to discuss this with a woman that he lied and said yes. So she said, 'Then you don't have PD'. That tells it all. This was head of the Movement department at Columbia University hospital in NYC.

[Carolinagirl123 in reply to Donzim]

omg! that's terrible. my guy can get it up but it always doesnt stay up. and he has been able to achieve orgasm through creativity on my part. maybe we should have our men adjust their meds to maximze their interest and ability.

[Donzim in reply to Carolinagirl123]

Too much dopa is not a good thing due to its known side effects

[park_bear in reply to Carolinagirl123]

To you and gimba both - everything gets blamed on PD but the fact is we men lose testosterone production as we age. Testosterone can be added back, but it tends to promote prostate cancer and most older men have some. There is something better!:

"Group 1 was given testosterone undecanoate 160 mg/day, the second group was given propionyl -l-carnitine 2 g/day plus acetyl-l-carnitine 2 g/day ... Carnitines proved significantly more active than testosterone in improving nocturnal penile tumescence and International Index of Erectile Function score. Testosterone significantly increased the prostate volume (not good) ... carnitines did not. "

Those carnitines are non prescription supplements available over the net.

[Carolinagirl123 in reply to park_bear]

how did it work for you?

[park_bear in reply to Carolinagirl123]

Very well! I would not have recommended it otherwise.

[arwenmark]

Most implants work regardless of interest or ability to "get it up" as they say. They are manually pumped up with the pump implanted in the scrotum. And it stays up till you let it down again.

[silvestrov]

Being a male I have given this some thought because when I was temporarily affected by various toxins...herbicides, insecticides....that induced temporary parkinsonism, I too had ED. My approach to this topic is to apply herbs....which have been proven to work together and are good for ED (and PD). The most obvious choice of herbs to treat both PD and ED is mucuna pruriens:

Mucuna pruriens Reduces Stress and Improves the Quality of Semen in Infertile Men

ncbi.nlm.nih.gov/pmc/articl...

HP-200 also known as Zandopa has been tested on PD patients:

An alternative medicine treatment for Parkinson's disease: results of a multicenter clinical trial. HP-200 in Parkinson's Disease Study Group.

"HP-200, developed from an alternative medicine source, Ayurveda, was found to be an effective treatment for patients with Parkinson's disease."

ncbi.nlm.nih.gov/pubmed/939...

A Water Extract of Mucuna pruriens Provides Long-Term Amelioration of Parkinsonism with Reduced Risk for Dyskinesias

ncbi.nlm.nih.gov/pmc/articl...

The best herbal aphrodisiac, yohimbine, has been shown to exacerbate PD related anxiety disorders:

Parkinson's disease: a preliminary study of yohimbine challenge in patients with anxiety.

"The one patient with PD and a history of major depression alone developed a panic attack. Regardless of their history of anxiety or depression, parkinsonian patients demonstrated a vulnerability to yohimbine-induced somatic symptoms."

ncbi.nlm.nih.gov/pubmed/103...

Yohimbine does affect the dopaminergic system:

Yohimbine interacts with the dopaminergic system to reverse sexual satiation: further evidence for a role of sexual motivation in sexual exhaustion.

ncbi.nlm.nih.gov/pubmed/103...

So the question is, which herb can be safely paired with mucuna pruriens? (And all the answers are Indian herbs.)

MUSLI (SAFED MUSLI):

A Blend of Chlorophytum Borivilianum and Velvet Bean Increases Serum Growth Hormone in Exercise-Trained Men

"Chlorophytum borivilianum, also known as Safed Musli, is a tropical herb with many therapeutic applications within Ayurvedic medicine. Some of these purported benefits include enhanced immunomodulatory function, anti-tumor, anti-mutagenic and chemomodulatory effects, amelioration of diabetic complications, reduction in joint pain and rheumatoid arthritis, aphrodisiac qualities, and spermatogenic properties that many help with erectile dysfunction and impotency. Many of these enhanced physiological benefits may stem from its supported hypolipidemic and antioxidant properties. For more information on the purported benefits of chlorophytum borivilianum, readers are referred to the review by Thakur et al."

ncbi.nlm.nih.gov/pmc/articl...

Effects of Chlorophytum borivilianum on sexual behaviour and sperm count in male rats.

ncbi.nlm.nih.gov/pubmed/184...

There are other herbs which work well with mucuna pruriens including Tribbulus terrestris - for women:

Tribulus terrestris for treatment of sexual dysfunction in women: randomized double-blind placebo - controlled study

"Tribulus terrestris may safely and effectively improve desire in women with hypoactive sexual desire disorder. Further investigation of Tribulus terrestris in women is warranted."

ncbi.nlm.nih.gov/pmc/articl...

Effects and Mechanism of Action of a Tribulus terrestris Extract on Penile Erection

"Accordingly, the T. terrestris extract may improve erectile function."

ncbi.nlm.nih.gov/pmc/articl...

Comparative evaluation of the sexual functions and NF-κB and Nrf2 pathways of some aphrodisiac herbal extracts in male rats.

"These results demonstrate for the first time that Mucuna, Tribulus and Ashwagandha supplementation improves sexual function in male rats via activating Nrf2/ HO-1 pathway while inhibiting the NF-κB levels. Moreover, Tribulus terrestris extract was found to be more bioavailable from Ashwagandha extract followed by Mucuna extract. Schematic representation of the mode of action of some aphrodisiac herbal extracts to improve sexual functions."

ncbi.nlm.nih.gov/pubmed/275...

Tribulus terrestris is a reversible MAO-A inhibitor and should be used with caution for those taking PD MAO-B inhibitors like selegiline and deprenyl.

[Carolinagirl123 in reply to silvestrov]

so how are you doing today and have you found any particular product to be more helpful than others?

[silvestrov in reply to Carolinagirl123]

Yohimbine is the best but not to be used systemically. I do not have anxiety issues and yohimbine makes me anxious...the more you take the anxiety is induced - not my first choice. I take Tribulus terrestris, Safed musli and mucuna pruriens.

Ginsing is also good:

Korean red ginsing for women:

ncbi.nlm.nih.gov/pubmed/201...

Korean red ginsing for men:

ncbi.nlm.nih.gov/pubmed/187...

Korean red ginsing in a PD mouse model:

ncbi.nlm.nih.gov/pmc/articl...

[Serenity_finaly-1 in reply to silvestrov]

Boy that is a lot of learning just to be able to perform. This is what I have been trying to say. I did not even have to think about it 20 years ago.😎

[Quipu]

Cialis 20mg works for me.

[Coblrman in reply to Quipu]

My urologist tested me on a daily maintenance dose of cialis which worked real well for ED and enlarged prostate but is expensive. A very cheap alternative is niacin.

[Quipu in reply to Coblrman]

It is expensive. I get them through CanadaDrugs.com at a very reasonable price.