Hi, I am Roy and I was diagnosed with PD about 6 years ago but the symptoms had been there for at least 2 years before. My then neurologist put me on Cardiodopa 300mg. My GP thought the side effects outweighed the benefits and we tried homeopathic remedies.At the time I was being treated for high blood pressure and my cardiologist changed my meds to Perindopril/amlodopine without explanation. After a year my muscle stiffness began to be a problem and I was recommended t a different neurologist who put me on Azilect (rasagaline), pramipexol and Madopar (the latter at 250mg per day). A year later this specialist told me he would not think I had PD if he did not already know it . My movements were fluid, the slight tremor in my left foot was seldom present! He was amazed! Until today, my lifestyle has not been seriously affected ( I continue to be an active travel photographer) except when the weather turns hot and humid and when, for a short time, I stopped taking Azilect due to the fact that its high cost is not covered by my state insurance.
I often wondered why I am so fortunate! My PD is not progressing and I have not had to increase meds ever. I once read about the possible beneficial effects of Perindopril. The posts regarding Perindopril are what has drawn my attention to this community!
I wonder if this is indeed a possible explanation.