Just started taking Comtan (along with usual sinemet) and find my off-times are drastically increased so that there's very little on-time. Didn't expect Comtan to have the opposite effect of what it's supposed to do. Also more foot dystonia (cramping) forcing me to walk on the outside edge--OUCH. And more dizziness and fatigue. None of the digestive side effects. Anyone else with similar Comtan side effects? We're all different!!
On another note related to off times: Has anyone tried taking Tums (antacid) to help with delayed stomach empyting and therefore getting delayed or reduced on time with sinemet?
I take sinemet 5 times a day ER and IR 25/100 for a total of 10 per day. It's the only PD med that's really worked for me. Have taken it for most of the 13 years I've been diagnosed--gradually increasing over those years. Have been able to continue skiing and riding motorcycle. Now the unpredictableness of these off times is preventing me from even driving at times.