I'm trying to replace Carbidopa/Levadopa with Mucuna Puriens. Wondering if I need to slowly reduce dosage or would it be ok to stop one 25/l00 as long as I'm still getting L-dopa from M.P.?
Medication: I'm trying to replace Carbidopa... - Cure Parkinson's
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Dottie2
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Have you worked out the dosage of Mucuna you will require and how often?
The two people I know who are only using Mucuna have to take a very specific dosage every 90 minutes. What does your neurologist say about this? Or are you working with a naturopath or other physicians?
Where do you live....US, UK, Canada?
Dottie2 in reply to
I live in US. So far I haven't found a neurologist that is interested in or knows anything about Mucuna so I am just experimenting. So far all I have is a really strong tremor in both arms & legs, but have been on Sinemet about 6 yrs. Makes me nauseated and causes dyskinesia . No dyskinesia on Mucuna.
How many sinemet a day for 6 years have you been taking ?
25/250 3x/d is what it took to get some relief from my tremor
In the last yr. or so started trying to slowing decrease amount due to side effects. For awhile have been taking l-l/2 10/l00. Now trying to replace more with MP.
My Husband has been taking Carb/Levo 25-100 for 3 years now. At first it helped his symptoms, but now, even up to 1 pill 5 times a day, it does absolutely nothing. Would love to go off of it because the side effects along with all his other meds are worse, dizziness, balance, etc. We tried going off by taking one dose away every 2 days, but didn't get past the second day without him having trouble at night with sleeping.Which is odd, because he takes a sleep aid. Medication is very frustrating for us and every time we talk to the neurologist about having difficulty, he adds another pill, which I usually end up taking my husband off of it because of the side effects after about 2 weeks, then he pushes the DBS surgery.
ruthgt in reply to
I also try to use mucuna I used c./l 25/250 I have a very swollen left leg and ankle .only the left leg .does anyone of you heard about sach a problem
I have been on MP since 2013. I never took allopathy ; though it was recommended in 2010 July, when I was diagnosed having PD . I managed with exercise, yoga, cycling, breathing exercise, walking and w/o any medication. Even now I take only Indian MP ( Vaidhayratnam Kerala INDIA , pl search google , you will get full details , you can order ON LINE, they ship world wide ) powder 1 TBS x 3 times per day in empty stomach with normal drinking water 200 ml with 1/2 fresh lemon juice for quick action in 30 Mins (must; otherwise it will not work, I understand , same is the case with Allopathy ; this is for better absorption and quick action ). This gives 2.5 hrs ON time. In addition to this I take 250mg x2 Ashwagandha Tabs & 250mg x2 Shudha Gugulu from Himalaya Wellness Products from Bangalore INDIA ; with 500 ml warm milk; once in morning 2 hrs before break & at before bed time after dinner fast this can also be ordered ON LINE. Please Google search for Benefits of Ashwagandha ; established reversal of PD in animal model. If you have any constipation you can buy Bruhath Tripala from Vaidyaratnam, very effective herb, one TBS in warm water 200 ml at bed time will take care of constipation, one can adjust the dosage, depending on ones condition.
If you need any more information or help , please let me know.
Reg
Ramuu
Ramuu
What is Allopathy?
Your reply is very interesting.
Allopathic medication viz. , Sinemet, L- dopa etc, which are also called as western medication or synthetic medication
Ok
Thanks.
I will need to look into that. My husband is taking Sinemet and Comtan. He is having fluctuations in BP and irregular heart beat.
I know both are caused by the medications. I know the Medication is the cause because of the times of the readings. I did look into it while we were in Singapore. At that time (a few years ago) it was not allowed for use in Singapore .
We live in Canada. I will need to study dosage etc. Any suggestions are greatly appreciated.
Thanks
Dosage depends on condition, one can make trial , no harm. Start with 1 TBS x 3 times a day ( please note, it has to be taken empty stomach only, squeeze half lemon, add about 200 to 250 ml normal drinking water , mix it well and consume ) ; slowly increase the dosage , only if required, but should not exceed 10 grams per dosage.
God Bless You & Your Family
Regards
Ramuu
The Zadopa has a scoop that say its about 7.5g. It takes 2 scoops for me to get relief from tremors.
Are you saying I should not take more than 10g per dose?
Two scoops is 15g. Concerned if I'm taking too much.
My Ayurvedic Doctor advised me not to take more than 10 g, and generally not more than 3 to max 4 times per day, as he has seen many of his patients developed induced dyskinesia , but when he reduced dosage, they were relived of dyskinesia. I feel it is different experience from person to person. Please adjust your dosage No harm.
Thank you so much for all the information. I will be looking everything up. At the moment am just taking 4 capsules of 15% l-dopa along with Mucuna tincture drops. Also just started on CBD oil.
Good , our policy should be to take minimum medication, so that our leftover cells don't become lazy and dormant. Please look for elasticity of Brian , there billions of back up cells which will take over provided we give them enough opportunity. We have to undergo pain , not easier than said !!. We have to try often to go on medication holiday, so that we can check whether our body can withstand. This is possible with Ayurvaidic medication, as they are less potent than Allopathic medication.
God bless you and your family
Dottie2 - where did you get the CBD oil and which country are you in?
Here is one site you can check out
I'm in US
Dottie2, have you noticed any benefit from taking this type of CBD oil?
I've just started using it. I believe they say it has a buildup effect. I do think shortly after I take it I notice some relief with my tremor, but am experimenting with how much to take.
Tremor is my only symptom, so thats all I can address. You probably know this has just come available
What is cbd oil?
in reply to Ramuu
Hi Ramuu,\
I was unable to find Mucuna P at Vaidhayratam, is there an other name I can try? please let me know.
thnks
Ramuu in reply to
It is called as KapiKachu Choornam; it is in Sanskrit - Vedic Language. Please go step by step as following :
Click on Choornam& Gulikas tab and select Choornam , this will take you to products display.
On your Ipad/PC/Laptop press Ctrl & F or Function search , in search box type kapi , it will take you to the product.
If you need any help, please let me know, please feel free to mail me : ramanath.tarekere@gmail.com
I started using MP a year ago with, I think, great success and I believe it delayed me having to take more conventional medication. A few weeks ago, I started to take prescribed meds but I have negotiated a lower dose than originally prescribed and I'm supplementing it with MP (I use Zandopa). I agree - experimenting is key. We're the ones living with this. My experience has been that while I am grateful to have the resource of a very knowledgeable neuro, who has a particular interest in Parkinson's, he is understandably focused on conventional medication because that is his training. He also has a crowded clinic and little time. As I am going to be stuck with PD for the rest of my life, I've done a lot of research. My conclusion is not original and it is that exercise, supplements and medication will help me manage this as well as I can.
When you were only on MP, how do you handle being out away from home?... mixing with water, etc.
I used the capsules!
So Zandopa has a capsule. How many did you have to take?
Do you have tremors
Sorry Dottie - I use MP capsules - the 1000mg from natural herbal health when I'm out and about and need something portable. I use the Zandopa powder - which I get on eBay - at home. The dose is something I experimented with. I have a slight tremor but my main symptom is weakness down my left side and a terribly stiff hand. The tremor isn't that bothersome yet but the Zandopa definitely helps it.
Both strategies should work fine - but check how much L-dopa is in each MP capsule / pill ... and match to C/L level
Dottie ,
I remember your posting , you indicated that you have bad tremor in left hand & left leg; if it is yes , please try the following, my hand tremor has considerably reduced !! If you don't have any problem, pl ignore my posting.
For Hands & Legs Tremor
Adho Mukha Svanasana :downward-facing dog Pose ; please see link :en.wikipedia.org/wiki/Adho_...
PS : Put pressure on both hands and legs ; do it only in empty stomach; best time early morning or in the evening after 4 hrs of Lunch, 10 counts x 5 times to 10 times slowly increase every day by 2-3 counts . Take deep breath slowly deep inhale & exhale .
For only Hands Tremor
Bhujangasana : Cobra Pose : Please see link : en.wikipedia.org/wiki/Bhuja...
PS : Same as above
God Bless You & Your Family
Regards
Ramuu
Mucuna is levodopa without the carbidopa. Without the carbidopa you need a higher dose of the mucuna to get it past the blood brain barrier. The higher dose can cause nausea. If you can make it work for you, great. If not you can mix and match with some of each, getting however much carbidopa you need to make it work.
I am taking both Mucuna Pruriens and ropinirole, and find the combination works well for me. I found a 40% Mucuna preparation, which is the strongest I have found on the market. I do not know what Zandopa concentration is, but it works well, and faster, as well.
The ropinirole worked fine at first, then the effects wore off to where it only helps me for about 2 hours a night. With the MP and Zandopa, I can sleep most of the night. I am also having my leg vein reflux taken care of, which the doctor tells me will greatly help, if not stop the RLS.
God bless!
Hi Dottie2, we are now 3 years on from your post and my partner, (early stage PD who started Prolopa (Madopar) a year ago) is thinking of also progressively replacing the Prolopa with Mucuna. What has been your experience? Would you recommend this approach?
I had pretty good luck with mucuna, but the taste made me shutter. Maybe it wouldn’t bother you. Think it would be worth a try. But about 2yrs ago after tremors went to both arms and legs I was miserable. After much prayer i decided to have DBS done. I am now tremor free... praising God. Sometimes I Notice a tiny shaking but insignificant. I live in Houston area in Texas. Prayers and best wishes for you and your partner. Talk to your dr about DBS if you haven’t already. It was a miracle for me. Took me about a yr or so to get adjustment right. Don’t know your partners age butler I just turned 78
Thanks so much Dottie2. I am very grateful for your response. My partner is 73. I am so glad that DBS has been so good for you. I send you a big hug and Much happiness. DreamRain
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