•Take your medications precisely on time. Missing a dose by as little as 15 to 30 minutes can result in a sudden "off" period which may last for hours. If you have missed a Sinemet dose by 30 minutes or less, chewing the tablets (tastes like chalk) can sometimes hasten the benefits. Perhaps this is because of more rapid absorption through the lining of the mouth. Do not chew Sinemet CR or the other PD drugs.
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